FZ7-21 Inhibitor

Name: FZ7-21 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5763530
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5763530

Fz7-21 is a peptide antagonist of FZD7. It antagonises WNT3A-induced Wnt-beta-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/beta-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100nM) or transfected with a construct… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fz7-21, Inhibitor

Full Product Name

Fz7-21

Product Gene Name

Fz7-21, inhibitor

Product Synonym Names

(Ac)-LPSDDLEFWCHVMY-NH2

Form/Format

Solid. Powder

Purity/Purification

99.80%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

1796.05

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C83H114N18O23S2

SMILES

CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

CAS Number

2247635-23-8

Product Categories/Family for Fz7-21, inhibitor

Cytoskeletal Signaling; Stem Cells

Product References and Citations for Fz7-21, inhibitor

Nile AH, et al. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat Chem Biol. 2018 Sep;14(9):902.

Other Notes

Small volumes of Fz7-21, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fz7-21 purchase

MBS5763530 is an inhibitor targeting Fz7-21.