Glucagon (19-29), acetate Inhibitor

Name: Glucagon (19-29), acetate Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5789459
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5789459

Glucagon (19-29), Human acetate a COOH-terminal fragment processed from glucagon, is a potent and efficient inhibitor of insulin secretion. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Glucagon (19-29), acetate, Inhibitor

Full Product Name

Glucagon (19-29), Human acetate

Purity/Purification

98%

Preparation and Storage

Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years

Molecular Weight

1412.57

SMILES

CC(O)=O.O=C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Formula

C63H93N15O20S

Target

Glucagon Receptor

Solubility

(<1mg/mL refers to the product slightly soluble or insoluble)

In_vitro

At concentrations ranging from 0.01 to 1000 pM, glucagon 19-29 dose-dependently (ID50 = 1 pM) inhibited by 80-100% the insulin release triggered by glucose, glucagon, glucagon-like peptide-1-(7-36) amide (tGLP-1), or glibenclamide, but not that induced by carbachol[1].

Product Categories/Family for Glucagon (19-29), acetate, inhibitor

GPCR/G Protein

Product References and Citations for Glucagon (19-29), acetate, inhibitor

1 Dall S e al Miniglucago (glucago 19-29) poten an efficien inhibito o secretagogue-induce insuli releas throug Ca2 pathway Bio Chem 199 Ap 16 74(16):10869-76.
2 Pavoin C e al Miniglucago [glucagon-(19-29) i componen o th positiv inotropi effec o glucagon A Physiol 199 May 60( P 1):C993-9.
3 Dall S e al Miniglucago (glucago 19-29) nove regulato o th pancreati isle physiology Diabetes 200 Feb 1(2):406-12.

Other Notes

Small volumes of Glucagon (19-29), acetate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Glucagon (19-29), acetate purchase

MBS5789459 is an inhibitor targeting Glucagon (19-29), acetate. Also known as Glucagon (19-29), Human acetate.