[LYS5,MeLeu9,NLE10]-NKA(4-10) Inhibitor

Name: [LYS5,MeLeu9,NLE10]-NKA(4-10) Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5763881
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5763881

Highy selective and potent NK2 receptor agonist (IC50 = 6.1nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10nM respectively). More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

[Lys5,MeLeu9,Nle10]-NKA(4-10), Inhibitor

Full Product Name

[Lys5,MeLeu9,Nle10]-NKA(4-10)

Product Gene Name

[Lys5,MeLeu9,Nle10]-NKA(4-10), inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

804

Solubility

Water: 1mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C39H65N9O9

SMILES

CCCC[C@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(N)=O

CAS Number

137565-28-7

Target & IC50

NK2

Product Categories/Family for [Lys5,MeLeu9,Nle10]-NKA(4-10), inhibitor

GPCR/G Protein; Neurokinin Receptor; Neuronal Signaling

Product References and Citations for [Lys5,MeLeu9,Nle10]-NKA(4-10), inhibitor

Chassaing et al (1991) Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides 19 91 PMID:
Chassaing et al (1991) Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides 19 91 PMID:
Matuszek et al (1998) An investigation of tachykinin NK2 receptor subtypes in the rat. Eur.J.Pharmacol. 352 103 PMID:
Matuszek et al (1998) An investigation of tachykinin NK2 receptor subtypes in the rat. Eur.J.Pharmacol. 352 103 PMID:
Burcher et al (2008) Tachykinin NK2 receptor and functional mechanisms in human colon: changes with indomet. and in diverticular disease and ulcerative colitis. J.Pharmacol.Exp. Ther. 324 170 PMID:
Burcher et al (2008) Tachykinin NK2 receptor and functional mechanisms in human colon: changes with indomet. and in diverticular disease and ulcerative colitis. J.Pharmacol.Exp. Ther. 324 170 PMID:

Other Notes

Small volumes of [Lys5,MeLeu9,Nle10]-NKA(4-10), inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for [Lys5,MeLeu9,Nle10]-NKA(4-10) purchase

MBS5763881 is an inhibitor targeting [Lys5,MeLeu9,Nle10]-NKA(4-10).