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KYL Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5763893

EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 uM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34uM). Prevents AbetaO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KYL, Inhibitor
Full Product Name
KYL
Product Gene Name
KYL, inhibitor
Product Synonym Names
KYL
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
1465.75
Solubility
Water: 2mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C74H108N14O17
CAS Number
676657-00-4

Product References and Citations for KYL, inhibitor

Lamberto et al (2012) Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor. Biochem. J. 445 47 PMID:
Lamberto et al (2012) Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor. Biochem. J. 445 47 PMID:
Vargas et al (2014) EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-beta oligomers. PLoS One. 9 e92309 PMID:
Vargas et al (2014) EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-beta oligomers. PLoS One. 9 e92309 PMID:

Other Notes

Small volumes of KYL, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KYL purchase

MBS5763893 is an inhibitor targeting KYL.
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