[cPP1-7,NPY19-23, Ala31, Aib32,Gln34]-hPancreatic Polypeptide Inhibitor

Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51nM respectively, Ki at Y5 = 0.1 - 0.15nM). Stimulates food intake in vivo.

Cabrele et al (2000) The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats. J. Biol.Chem. 275 36043 PMID:
Cabrele et al (2000) The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats. J. Biol.Chem. 275 36043 PMID:
Dumont et al (2005) BODIPY-conjugated neuropeptide Y ligands: new fluorescent tools to tag Y1, Y2, Y4 and Y5 receptor subtypes. Br.J.Pharmacol. 146 1069 PMID:
Dumont et al (2005) BODIPY-conjugated neuropeptide Y ligands: new fluorescent tools to tag Y1, Y2, Y4 and Y5 receptor subtypes. Br.J.Pharmacol. 146 1069 PMID:

Small volumes of [cPP1-7,NPY19-23, Ala31, Aib32,Gln34]-hPancreatic Polypeptide, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5763961 is an inhibitor targeting [cPP1-7,NPY19-23, Ala31, Aib32,Gln34]-hPancreatic Polypeptide. Also known as [cPP1-7,NPY19-23, Ala31, Aib32,Gln34] - hPancreatic Polypeptide.