Dynaminy peptide, myristoylated Inhibitor

Control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibitory peptide, has no significant effect on GABAA receptor-mediated miniature IPSPs.

Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynaminutes at a single site that defines a new SH3 binding consensus sequence. J. Biol.Chem. 272 13419 PMID:
Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynaminutes at a single site that defines a new SH3 binding consensus sequence. J. Biol.Chem. 272 13419 PMID:
Kittler et al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972 PMID:
Kittler et al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972 PMID:
Nong et al (2003) Glycine binding primesnMDA receptor internalization. Nature 422 302 PMID:
Nong et al (2003) Glycine binding primesnMDA receptor internalization. Nature 422 302 PMID:

Small volumes of Dynaminy peptide, myristoylated, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5764035 is an inhibitor targeting Dynaminy peptide, myristoylated. Also known as Dynamin inhibitory peptide, myristoylated (control).