[Phe8psi(CH-NH)-Arg9]-Bradykinin Inhibitor

Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin (Cat No. 3004) in vivo.

Drapeau et al (1988) [Phe8Psi(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II. Eur.J.Pharmacol. 155 193 PMID:
Drapeau et al (1988) [Phe8Psi(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II. Eur.J.Pharmacol. 155 193 PMID:
Marceau et al (2002) Kinin receptors: functional aspects. Int.Immunopharmacol. 2 1729 PMID:
Marceau et al (2002) Kinin receptors: functional aspects. Int.Immunopharmacol. 2 1729 PMID:
Leeb-Lundberg et al (2005) International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27 PMID:
Leeb-Lundberg et al (2005) International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27 PMID:

Small volumes of [Phe8psi(CH-NH)-Arg9]-Bradykinin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5764070 is an inhibitor targeting [Phe8psi(CH-NH)-Arg9]-Bradykinin.