[Ala1,3,11,15]-Endothelin Inhibitor

Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).

Nakamichi et al (1992) Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ETBiochem. Biophys.Res.Commun. 182 144 PMID:
Nakamichi et al (1992) Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ET1. Biochem. Biophys.Res.Commun. 182 144 PMID:
Panek et al (1992) Endothelin and structurally related analogs distinguish between endothelin receptor subtypes. Biochem. Biophys.Res.Commun. 183 566 PMID:
Panek et al (1992) Endothelin and structurally related analogs distinguish between endothelin receptor subtypes. Biochem. Biophys.Res.Commun. 183 566 PMID:

Small volumes of [Ala1,3,11,15]-Endothelin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5764093 is an inhibitor targeting [Ala1,3,11,15]-Endothelin.