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SAH-EZH2 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764108

EZH2/EPP interaction inhibitor (Kd = 320nM). Suppresses EZH2 expression and H3K27 trimethylation by PCR2 complex. Arrests proliferation and induces monocyte to macrophage differentiation of MLL-AF9 leukemia cell line. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SAH-EZH2, Inhibitor
Full Product Name
SAH-EZH2
Product Gene Name
SAH-EZH2, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
3432.05
Solubility
Water: 1mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C155H256N48O40
CAS Number
1453222-26-8

Product References and Citations for SAH-EZH2, inhibitor

Kim et al (2013) Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer. Nat.Chem. Biol. 9 643 PMID:
Kim et al (2013) Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer. Nat.Chem. Biol. 9 643 PMID:
Kim et al (2015) SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZHNat.Med. 21 1491 PMID:
Kim et al (2015) SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2. Nat.Med. 21 1491 PMID:

Other Notes

Small volumes of SAH-EZH2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAH-EZH2 purchase

MBS5764108 is an inhibitor targeting SAH-EZH2.
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