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SAH-SOS1A Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764109

KRas/son of sevenless 1 (SOS1) interaction inhibitor. Binds within nucleotide binding pocket of KRas (Kd values are 106 - 176nM for wild type KRas and various KRas mutants). Inhibits nucleotide binding to KRas in a concentration dependent manner. Displays… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SAH-SOS1A, Inhibitor
Full Product Name
SAH-SOS1A
Product Gene Name
SAH-SOS1A, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
2187.53
Solubility
Water: 1mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C100H159N27O28
CAS Number
1652561-87-9

Product References and Citations for SAH-SOS1A, inhibitor

Leshchiner et al (2015) Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Proc.Natl. Acad.Sci.USA. 112 1761 PMID:
Leshchiner et al (2015) Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Proc.Natl. Acad.Sci.USA. 112 1761 PMID:

Other Notes

Small volumes of SAH-SOS1A, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAH-SOS1A purchase

MBS5764109 is an inhibitor targeting SAH-SOS1A.
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