SAHM1 Inhibitor

Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.

Ashley et al (2015) Notch signaling promotes osteoclast maturation and resorptive activity. J Cell Biochem 116 2598 PMID:
Ashley et al (2015) Notch signaling promotes osteoclast maturation and resorptive activity. J Cell Biochem 116 2598 PMID:
Bagheri et al (2018) Notch pathway is active during osteogenic differentiation of human bone marrow mesenchymal stem cells induced by pulsed electromagnetic fields. J. Tissue Eng.Regen.Med. 12 304 PMID:
Bagheri et al (2018) Notch pathway is active during osteogenic differentiation of human bone marrow mesenchymal stem cells induced by pulsed electromagnetic fields. J. Tissue Eng.Regen.Med. 12 304 PMID:
KleinJan et al (2018) The Notch pathway inhibitor stapled a-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma. J. Allergy Clin.Immunol. 142 76 PMID:
KleinJan et al (2018) The Notch pathway inhibitor stapled a-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma. J. Allergy Clin.Immunol. 142 76 PMID:

Small volumes of SAHM1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5764110 is an inhibitor targeting SAHM1.