TRV-120027 Inhibitor – TFA

Name: TRV-120027 Inhibitor; TFA; MyBioSource
Brand: MyBioSource
SKU: MBS5764135
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764135

TRV120027 TFA is a beta-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages beta-arrestins while blocking G-protein signaling. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TRV-120027 TFA, Inhibitor

Full Product Name

TRV-120027 TFA

Product Gene Name

TRV-120027, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

1040.1

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C45H68F3N13O12

Target & IC50

the angiotensin II receptor type 1

Product Categories/Family for TRV-120027, inhibitor

Endocrinology/Hormones; RAAS

Product References and Citations for TRV-120027, inhibitor

Boerrigter G, et al. TRV120027, a novel beta-arrestin biased ligand at the angiotensin II type I receptor, unloads the heart and maintains renal function when added to furosemide in experimental heart failure.Circ Heart Fail. 2012 Sep 1;5(5):627-3Epub 2012 Aug 13.
Boerrigter G, et al. TRV120027, a novel beta-arrestin biased ligand at the angiotensin II type I receptor, unloads the heart and maintains renal function when added to furosemide in experimental heart failure.Circ Heart Fail. 2012 Sep 1;5(5):627-34. Epub 2012 Aug 13.
Liu CH, et al. Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling.Nat Commun. 2017 Feb 9;8:14335.
Liu CH, et al. Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling.Nat Commun. 2017 Feb 9;8:14335.

Other Notes

Small volumes of TRV-120027, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRV-120027 purchase

MBS5764135 is an inhibitor targeting TRV-120027. Also known as TRV-120027 TFA.