Z-WEHD-FMK Inhibitor

Name: Z-WEHD-FMK Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5764137
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764137

Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6uM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Z-WEHD-FMK, Inhibitor

Full Product Name

Z-WEHD-FMK

Product Gene Name

Z-WEHD-FMK, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

763.77

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C37H42FN7O10

CAS Number

210345-00-9

Target & IC50

Caspase-1

Product Categories/Family for Z-WEHD-FMK, inhibitor

Apoptosis; Caspase; Proteases/Proteasome

Product References and Citations for Z-WEHD-FMK, inhibitor

Kamada S, et al. Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases.Cell Death Differ. 1997 Aug;4(6):473-8.
Kamada S, et al. Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases.Cell Death Differ. 1997 Aug;4(6):473-8.
Yang D, et al. Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish.Nat Commun. 2018 Aug 3;9(1):3052.
Yang D, et al. Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish.Nat Commun. 2018 Aug 3;9(1):3052.
Ferko MA, et al. Effects of metal ions on caspase-1 activation and interleukin-1beta release in murine bone marrow-derived macrophages.PLoS One. 2018 Aug 23;13(8):e0199936.
Ferko MA, et al. Effects of metal ions on caspase-1 activation and interleukin-1beta release in murine bone marrow-derived macrophages.PLoS One. 2018 Aug 23;13(8):e0199936.
Newman ZL, et al. CA-074Me protection against anthrax lethal toxin. Infect Immun. 2009 Oct;77(10):4327-36.
Newman ZL, et al. CA-074Me protection against anthrax lethal toxin. Infect Immun. 2009 Oct;77(10):4327-36.

Other Notes

Small volumes of Z-WEHD-FMK, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Z-WEHD-FMK purchase

MBS5764137 is an inhibitor targeting Z-WEHD-FMK.