p53 tumor suppressor fragment Inhibitor

Solid. Powder

98.00%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

1066.3

DMSO: >=53.3mg/mL
DMSO: >=53.3mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)

C41H67N11O14S4

NC(CCCCN)C(NC(CC1=CC=C(O)C=C1)C(NC(CCSC)C(NC(CS)C(NC(CC(N)=O)C(NC(CO)C(NC(CO)C(NC(CS)C(NC(CCSC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O

p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation. p53 has many mechanisms of anticancer function and plays a role in apoptosis, genomic stability, and inhibition of angiogenesis. In its anti-cancer role, p53 works through several mechanisms: It can activate DNA repair proteins when DNA has sustained damage. It can induce growth arrest by holding the cell cycle at the G1/S regulation point on DNA damage recognition. It can initiate apoptosis, the programmed cell death if DNA damage proves to be irreparable [1][2][3].