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type II collagen fragment Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764255

Type II collagen is composed of a triple helix of three identical alpha chains. These molecules associate to form a fibril that is stabilized by intermolecular crosslinks1. Damage to the fibrillar meshwork, made up of primarily type II collagen (z 90-95%),… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
type II collagen fragment, Inhibitor
Full Product Name
type II collagen fragment
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
1471.61
Solubility
DMSO: >=147.1mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C65H102N18O21
SMILES
NCC(NC(CCC(O)=O)C(N1CCCC1C(NCC(NC(C(C)CC)C(NC(C)C(NCC(NC(CC2=CC=CC=C2)C(NC(CCCCN)C(NCC(NC(CCC(O)=O)C(NC(CCC(N)=O)C(NCC(N3C(C(NC(CCCCN)C(O)=O)=O)CCC3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
In Vitro
Type II collagen and aggrecan (a large, aggregating proteoglycan) are the two major components of the extracellular matrix of cartilage. The collagen, which is present in a fibrillar form, provides tensile strength whereas the aggrecan is responsible for compressive stiffness of cartilage3-5. Early damage to type II collagen is predominantly pericellular/ territorial suggests that in the majority of cases collagen damage was mediated by the chondrocyte.

Other Notes

Small volumes of type II collagen fragment, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for type II collagen fragment purchase

MBS5764255 is an inhibitor targeting type II collagen fragment.
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