Rosiptor Inhibitor

Name: Rosiptor Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5764290
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764290

Rosiptor (AQX-1125) is an orally-active and specific phosphatase SHIP1 activator with anti-inflammatory effects. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rosiptor, Inhibitor

Full Product Name

Rosiptor

Product Synonym Names

AQX-1125

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

321.5

Solubility

DMSO: 145mg/mL (451mM) Need ultrasonic and warming
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C20H35NO2

SMILES

C[C@](CC1)([C@@H](CC2)[C@H](CN)[C@H]1[C@@](C)(CC1)[C@@H](CO)C[C@H]1O)C2=C

CAS Number

782487-28-9

Cell Research

Cell Line: MOLT-4 cells and SHIP1-deficient Jurkat cells (IGF-1 stimulation) [1]. Concentration: 0.1, 1, 10uM. Incubation Time: 30 minutes

Product Categories/Family for Rosiptor, inhibitor

Phosphatase; Metabolic Enzyme/Protease

Product References and Citations for Rosiptor, inhibitor

Stenton GR, et al. Characterization of AQX-1125, a small-molecule SHIP1 activator: Part Effects on inflammatory cell activation and chemotaxis in vitro and pharmacokinetic characterization in vivo. Br J Pharmacol. 2013 Mar;168(6):1506-18.
Stenton GR, et al. Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis in vitro and pharmacokinetic characterization in vivo. Br J Pharmacol. 2013 Mar;168(6):1506-18.
Cross J, et al. AQX-1125, small molecule SHIP1 activator inhibits NSC-125066-induced pulmonary fibrosis. Br J Pharmacol. 2017 Sep;174(18):3045-3057.
Cross J, et al. AQX-1125, small molecule SHIP1 activator inhibits NSC-125066-induced pulmonary fibrosis. Br J Pharmacol. 2017 Sep;174(18):3045-3057.

Other Notes

Small volumes of Rosiptor, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rosiptor purchase

MBS5764290 is an inhibitor targeting Rosiptor.