NVP-LCQ195 Inhibitor

Name: NVP-LCQ195 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5764325
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764325

NVP-LCQ195 (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42nM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NVP-LCQ195, Inhibitor

Full Product Name

NVP-LCQ195

Product Gene Name

NVP-LCQ195, inhibitor

Product Synonym Names

LCQ-195

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

460.33

Solubility

DMSO: 100mg/mL (217.24mM)
Water: Insoluble
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C17H19Cl2N5O4S

SMILES

CS(=O)(=O)N1CCC(CC1)NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl

CAS Number

902156-99-4

In Vitro

Bortezomib-treatedmM patients whose tumours had high baseline expression of genes suppressed by LCQ195 had significantly shorter progression-free and overall survival than those with low levels of these transcripts in theirmM cells.

Product Categories/Family for NVP-LCQ195, inhibitor

Cell Cycle/Checkpoint; CDK

Product References and Citations for NVP-LCQ195, inhibitor

McMillin DW, Delmore J, Negri J et al. Molecular and cellular effects of multi-targeted cyclin-dependent kinase inhibition in myeloma: biological and clinical implications. Br J Haematol. 2011 Feb;152(4):420-32.

Other Notes

Small volumes of NVP-LCQ195, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NVP-LCQ195 purchase

MBS5764325 is an inhibitor targeting NVP-LCQ195.