JNJ-40411813 Inhibitor

Name: JNJ-40411813 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5764350
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764350

JNJ-40411813 (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147nM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

JNJ-40411813, Inhibitor

Full Product Name

JNJ-40411813

Product Gene Name

JNJ-40411813, inhibitor

Product Synonym Names

ADX-71149

Form/Format

Solid. Powder

Purity/Purification

99.57%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

344.88

Solubility

DMSO: 24mg/mL (69.59mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C20H25ClN2O

SMILES

CCCCn1ccc(N2CCC(CC2)c2ccccc2)c(Cl)c1=O

CAS Number

1127498-03-6

Product Categories/Family for JNJ-40411813, inhibitor

Neuroscience; GluR

Product References and Citations for JNJ-40411813, inhibitor

Cid JM, et al. Discovery of 1-Butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone (JNJ-40411813): A Novel Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor. J Med Chem. 2014 Aug 14;57(15):6495-512.

Other Notes

Small volumes of JNJ-40411813, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JNJ-40411813 purchase

MBS5764350 is an inhibitor targeting JNJ-40411813.