CMPDA Inhibitor

Name: CMPDA Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5764370
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764370

CMPDA is a positive allosteric modulator of AMPA receptors (EC50s: 45.4nM/63.4nM for GluA2i/GluA2o receptor). More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CMPDA, Inhibitor

Full Product Name

CMPDA

Product Gene Name

CMPDA, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

376.53

Solubility

DMSO: Soluble
(<1mg/ refers to the product slightly soluble or insoluble)

Formula

C16H28N2O4S2

SMILES

CC(S(NCCC1=CC=C(CCNS(C(C)C)(=O)=O)C=C1)(=O)=O)C

CAS Number

380607-77-2

In Vitro

CMPDA was nearly equipotent at modulating the two isoforms of GluA2 receptors, whereas CMPDB displayed a modest preference for the flip splice variant. CMPDA slowed the rate of deactivation of GluA2o receptors approximately 2-fold but had no effect on GluA2i receptor deactivation.

Product Categories/Family for CMPDA, inhibitor

Neuroscience; GluR

Product References and Citations for CMPDA, inhibitor

Timm DE, et al. Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol Pharmacol. 2011 Aug;80(2):267-80.
Timm DE, et al. Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol Pharmacol. 2011 Aug;80(2):267-80.

Other Notes

Small volumes of CMPDA, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CMPDA purchase

MBS5764370 is an inhibitor targeting CMPDA.