VCH-916 Inhibitor

MBS5764378 is an inhibitor targeting VCH-916. VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.

Abdelrahman S. Mayhoub. Hepatitis C RNA-dependent RNA polymerase inhibitors: A review of structure-activity and resistance relationships; different scaffolds and mutations. Bioorganic & Medicinal Chemistry. 2012, 20 (10): 3150-3161.
Abdelrahman S. Mayhoub. Hepatitis C RNA-dependent RNA polymerase inhibitors: A review of structure-activity and resistance relationships; different scaffolds and mutations. Bioorganic & Medicinal Chemistry. 2012, 20 (10): 3150-3161.
Debasis Dasa, Jian Honga, Shu-Hui Chena, et al. Recent advances in drug discovery of benzothiadiazine and related analogs as HCV NS5B polymerase inhibitors. Bioorganic & Medicinal Chemistry. 2011, 19(16): 4690-4703
Debasis Dasa, Jian Honga, Shu-Hui Chena, et al. Recent advances in drug discovery of benzothiadiazine and related analogs as HCV NS5B polymerase inhibitors. Bioorganic & Medicinal Chemistry. 2011, 19(16): 4690-4703
2. Pierre L Beaulieu. Recent advances in the development of NS5B polymerase inhibitors for the treatment,of hepatitis C virus infection. Informahealthcare. 2009, 19(2): 145-164
Pierre L Beaulieu. Recent advances in the development of NS5B polymerase inhibitors for the treatment,of hepatitis C virus infection. Informahealthcare. 2009, 19(2): 145-164

Small volumes of VCH-916, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.