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Paricalcitol Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764454

paricalcitol.is a vitamin D receptor agonist. It is used for the prevention and treatment,of secondary hyperparathyroidism associated with chronic renal failure. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Paricalcitol, Inhibitor
Full Product Name
Paricalcitol
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
416.64
Solubility
DMSO: 95mg/mL (228.02mM) Need ultrasonic
Ethanol: 12mg/mL (38.8mM) Need ultrasonic
Water: Insoluble
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C27H44O3
SMILES
CC(C=CC(C)C(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3)O)O)C
CAS Number
131918-61-1
In Vitro
paricalcitol.(300ng/kg/day) significantly decreases Tau and prevents LV dysfunction in mice. It reduces mRNA expression of ANP, fibronectin and collagen III in the TAC-pari mice [2].

Product Categories/Family for Paricalcitol, inhibitor

Product References and Citations for Paricalcitol, inhibitor

Martinez-Moreno JM, et al. In vascular smooth muscle cells paricalcitol.prevents phosphate-induced Wnt/beta-catenin activation. Am J Physiol Renal Physiol. 2012 Aug 8.
Martinez-Moreno JM, et al. In vascular smooth muscle cells paricalcitol.prevents phosphate-induced Wnt/beta-catenin activation. Am J Physiol Renal Physiol. 2012 Aug 8.
Meems LM, et al. The vitamin D receptor activator paricalcitol.prevents fibrosis and diastolic dysfunction in a murine model of pressure overload. J Steroid Biochem Mol Biol. 2012 Jul 16;132(3-5):282-289.
Meems LM, et al. The vitamin D receptor activator paricalcitol.prevents fibrosis and diastolic dysfunction in a murine model of pressure overload. J Steroid Biochem Mol Biol. 2012 Jul 16;132(3-5):282-289.

Other Notes

Small volumes of Paricalcitol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5764454 is an inhibitor targeting Paricalcitol.
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