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Teprotumumab Antibody – Human Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5818653

Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular alpha-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab reduces TSH-dependent… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Teprotumumab, Monoclonal Antibody
Full Product Name
Teprotumumab
Product Synonym Names
R 1507; HZN 001
Clonality
Monoclonal
Host
Human
Species Reactivity
IGF-1 receptor (IGF-1R)
Preparation and Storage
Powder: -20 degree C for 3 years | In solvent: -80 degree C for 1 year
Solubility
(< 1 mg/ml refers to the product slightly soluble or insoluble)
CAS Number
1036734-93-6
In_vitro
In fibrocytes, Teprotumumab (0-500ug/mL, 12 h) attenuates the actions of both IGF-1 and TSH. However, the mRNA abundance of IGF-1R and TSHR is unaffected by Teprotumumab after 24 hours[1].

Other Notes

Small volumes of anti-Teprotumumab antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Teprotumumab purchase

MBS5818653 is an antibody targeting Teprotumumab. Reactive in IGF-1 receptor (IGF-1R). Host: Human.
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