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Ordesekimab Antibody – Human Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5818817

Ordesekimab (AMG 714) is a human IgG1 kappa-anti-IL-15 (Interleukin Related) monoclonal antibody. Ordesekimab binds competitively to IL-15, inhibiting the interaction of IL-15 with the common gamma chain of the IL-2Rbeta and IL-15 receptor complex, but not… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ordesekimab, Monoclonal Antibody
Full Product Name
Ordesekimab
Product Synonym Names
AMG 714; PRV-015
Clonality
Monoclonal
Host
Human
Species Reactivity
IL-15
Preparation and Storage
Powder: -20 degree C for 3 years | In solvent: -80 degree C for 1 year
Solubility
(< 1 mg/ml refers to the product slightly soluble or insoluble)
CAS Number
879293-15-9
In_vitro
Theoretically, the simultaneous binding of Ordesekimab (AMG 714) to the Fcgamma receptor (R) IIIalpha expressed on natural killer (NK) cells and to the IL-15/IL-15Ralpha complex on cells such as monocytes may enable antibody-dependent cell-mediated cytotoxicity (ADCC) toward the IL-15Ralpha-expressing cells[1].

Other Notes

Small volumes of anti-Ordesekimab antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ordesekimab purchase

MBS5818817 is an antibody targeting Ordesekimab. Reactive in IL-15. Host: Human.
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