Rat Anti-MD-1 Monoclonal Antibody – Cat# MBS584120

MD-1 Antibody – Rat Monoclonal

Name: MD-1 Antibody; Monoclonal; Rat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS584120
Price: 685 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS584120

Product Description: The monoclonal antibody MD113 reacts with mouse MD-1. MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar… More details

$685 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MD-1, Monoclonal Antibody

Full Product Name

MD-1, Mouse, mAb MD113

Product Gene Name

anti-MD-1 antibody

Clonality

Monoclonal

Isotype

Rat IgG2b

Host

Rat

Species Reactivity

Mouse

Form/Format

1 ml (100 ug/ml) 0.2 um filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)

Preparation and Storage

Product should be stored at 4 degree C. Under recommended storage conditions, product is stable for one year.

Molecular Weight

17,906 Da

OMIM

605241

Applications Tested/Suitable for anti-MD-1 antibody

Flow Cytometry (FC/FACS), FS

Application Notes for anti-MD-1 antibody

Application Notes: The monoclonal antibody MD113 can be used for flow cytometry and functional studies. The monoclonal antibody cannot be used for Western blot and immunoprecipitation.
Application Use: For flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

Product References and Citations for anti-MD-1 antibody

1. Miyake, K et al; Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. J Immunol 1998, 161: 1348 2. Nagai, Y et al; Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide. Blood 2002, 99: 1699

Other Notes

Small volumes of anti-MD-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MD-1 purchase

MBS584120 is an antibody targeting MD-1. Also known as MD-1, Mouse, mAb MD113. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for MD-1. It may not necessarily be applicable to this product.

NCBI GI #

4321098

NCBI GeneID

9450

NCBI Accession #

AAC98152.2

UniProt Secondary Accession #

Q9UQC4

UniProt Related Accession #

O95711

NCBI Official Full Name

MD-1

NCBI Official Synonym Full Names

lymphocyte antigen 86

NCBI Official Symbol

LY86

NCBI Official Synonym Symbols

MD-1; MMD-1; dJ80N2.1

UniProt Protein Name

Lymphocyte antigen 86

UniProt Synonym Protein Names

Protein MD-1

UniProt Gene Name

LY86

UniProt Synonym Gene Names

MD1; Ly-86

UniProt Entry Name

LY86_HUMAN

NCBI Protein Information

lymphocyte antigen 86; ly-86; protein MD-1; MD-1, RP105-associated

UniProt Comments for MD-1

LY86: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.

Protein type: Secreted; Secreted, signal peptide; Apoptosis

Chromosomal Location of Human Ortholog: 6p25.1

Cellular Component: extracellular space; plasma membrane

Biological Process: cell proliferation; apoptosis; positive regulation of lipopolysaccharide-mediated signaling pathway; innate immune response; inflammatory response; humoral immune response

Research Articles on MD-1

1. DNA methylation of the LY86 gene is associated with obesity, insulin resistance, and inflammation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MD-1 antibody

Reference Product	PubMed Publications
TLR4 antibody	>23 publications with MD-1 and TLR4
CD180 antibody	>12 publications with MD-1 and CD180
CD14 antibody	>9 publications with MD-1 and CD14
LY96 antibody	>8 publications with MD-1 and LY96

Pathways associated with anti-MD-1 antibody

Products by Pathway	Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Toll Like Receptor 4 (TLR4) Cascade Pathway antibodies	Toll Like Receptor 4 (TLR4) Cascade Pathway Diagram
Toll-Like Receptors Cascades Pathway antibodies	Toll-Like Receptors Cascades Pathway Diagram

Diseases associated with anti-MD-1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>8 publications with MD-1 and Inflammation
Disease Models, Animal Antibodies	>3 publications with MD-1 and Disease Models, Animal
Liver Diseases Antibodies	>3 publications with MD-1 and Liver Diseases
Necrosis Antibodies	>3 publications with MD-1 and Necrosis
Lung Diseases Antibodies	>2 publications with MD-1 and Lung Diseases
Weight Loss Antibodies	>2 publications with MD-1 and Weight Loss
Respiratory Tract Diseases Antibodies	>2 publications with MD-1 and Respiratory Tract Diseases
Poisoning Antibodies	>1 publications with MD-1 and Poisoning
Fatty Liver Antibodies	>1 publications with MD-1 and Fatty Liver
Kidney Diseases Antibodies	>1 publications with MD-1 and Kidney Diseases