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LBP Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS584629

Product Description: LPS binding protein (LBP) is an approximately 60 kDa acute phase protein that is produced by hepatocytes. This protein strongly binds to LPS and has been shown to play an important role in the handling of LPS by the host. A number of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LBP, Protein
Full Product Name
LBP, Human, Peptide
Product Gene Name
LBP protein
Form/Format
Lyophilized, purified LBP-peptide from human LBP protein in PBS. The exact peptide amount is indicated on the label. Reconstitute the vial by pipetting sterile, endotoxin free phosphate buffered saline.
Preparation and Storage
Lyophilized product should be stored at 4 degree C. The stock solution should be stored in aliquots at -70 degree C in polypropylene tubes. LBP-peptide stock solution should never be thawed more than once. Repeated freeze and thaw cycles will cause loss of LBP-peptide activity. Under recommended storage conditions, product is stable for more than one year.
Molecular Weight
53,384 Da
OMIM
151990
Species
Human
Application Notes for LBP protein
Application Use: For neutralization of biological activity dilutions have to be made according to the amounts protein to be inactivated. Further dilutions should be made by using protein stabilized phosphate buffered saline, pH 7. (Never use fresh serum/plasma). Be aware: endotoxin will bind LBP-peptide.

Product References and Citations for LBP protein

Bucki, R et al; Extracellular Gelsolin binds lipoteichoic acid and modulates cellular response to proinflammatory bacterial wall components. J of Immunol. 2008, 181: 4936

Other Notes

Small volumes of LBP protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LBP purchase

MBS584629 is a protein targeting LBP. Also known as LBP, Human, Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for LBP. It may not necessarily be applicable to this product.

NCBI GI #
116242615
NCBI GeneID
3929
NCBI Accession #
P18428.3
UniProt Secondary Accession #
O43438; Q92672; Q9H403; Q9UD66; B2R938
UniProt Related Accession #
P18428
NCBI Official Full Name
Lipopolysaccharide-binding protein
NCBI Official Synonym Full Names
lipopolysaccharide binding protein
NCBI Official Symbol
LBP
NCBI Official Synonym Symbols
BPIFD2
UniProt Protein Name
Lipopolysaccharide-binding protein
Protein Family
Lipopolysaccharide-binding protein
UniProt Gene Name
LBP
UniProt Synonym Gene Names
LBP
UniProt Entry Name
LBP_HUMAN
NCBI Protein Information
lipopolysaccharide-binding protein; LPS-binding protein; BPI fold containing family D, member 2

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LBP protein

 Reference Product  PubMed Publications
 CD14 protein  >423 publications with LBP and CD14
 JUN protein  >390 publications with LBP and JUN
 TLR4 protein  >114 publications with LBP and TLR4
 LY96 protein  >18 publications with LBP and LY96
 CAMP protein  >9 publications with LBP and CAMP
 FOS protein  >4 publications with LBP and FOS
 STAT3 protein  >4 publications with LBP and STAT3

Pathways associated with LBP protein

 Products by Pathway  Pathway Diagram
 IL6-mediated Signaling Events Pathway antibodies  IL6-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
 Regulation Of Toll-like Receptor Signaling Pathway antibodies  Regulation Of Toll-like Receptor Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Toll Like Receptor 4 (TLR4) Cascade Pathway antibodies  Toll Like Receptor 4 (TLR4) Cascade Pathway Diagram
 Toll-Like Receptors Cascades Pathway antibodies  Toll-Like Receptors Cascades Pathway Diagram
 Toll-like Receptor Signaling Pathway antibodies  Toll-like Receptor Signaling Pathway Diagram

Diseases associated with LBP protein

 Disease Name  Pubmed Publications
 Pain Antibodies  >2953 publications with LBP and Pain
 Nervous System Diseases Antibodies  >2394 publications with LBP and Nervous System Diseases
 Inflammation Antibodies  >331 publications with LBP and Inflammation
 Necrosis Antibodies  >241 publications with LBP and Necrosis
 Sepsis Antibodies  >171 publications with LBP and Sepsis
 Cardiovascular Diseases Antibodies  >89 publications with LBP and Cardiovascular Diseases
 Liver Diseases Antibodies  >76 publications with LBP and Liver Diseases
 Obesity Antibodies  >67 publications with LBP and Obesity
 Carcinoma Antibodies  >48 publications with LBP and Carcinoma
 Brain Diseases Antibodies  >47 publications with LBP and Brain Diseases
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