• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IFN-gamma Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS584801

Monoclonal antibody F3 binds and neutralizes both natural and recombinant mouse gamma Interferon. Its binding and neutralizing activity has been demonstrated in vitro and in vivo. F3 antibodies have been demonstrated to be able to inhibit inflammatory… More details

$555 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IFN-gamma, Monoclonal Antibody
Full Product Name
IFN-gamma, Mouse, mAb F3
Product Gene Name
anti-IFN-gamma antibody
Clonality
Monoclonal
Host
Rat
Species Reactivity
Mouse
Form/Format
1 ml (100 mug/ml) 0.2 mum filtered protein G purified antibody solution in PBS, containing 0.1% bovine serum albumin.
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
Preparation and Storage
Should be stored at 4 degree C.
Under recommended storage conditions, product is stable for at least one year.
Molecular Weight
19,348 Da
3D Structure
ModBase 3D Structure for P01579
Endotoxin
The endotoxin concentration is < 24 EU/mg, determined with HIT302 LAL Assay.

Product Categories/Family for anti-IFN-gamma antibody

Autoimmunity; Infectious diseases
Applications Tested/Suitable for anti-IFN-gamma antibody
Functional Studies, Immunoassay, Immunoprecipitation (IP)
Application Notes for anti-IFN-gamma antibody
The typical starting working dilution is 1:50.

Product References and Citations for anti-IFN-gamma antibody

1. Armstrong, JA et al; Semi-micro, dye-binding assay for rabbit interferon. J Appl Microbiol 1971, 21: 723. 2. van Tiel, FH et al; Detection of Semliki Forest virus in cell culture by use of an enzyme immunoassay with peroxidase-labeled monoclonal antibodies specific for glycoproteins E1 and E2. J Clin Microbiol 1984, 20: 387. 3. Dijkmans, R et al; Heterogeneity of Chinese hamster ovary cell-produced recombinant murine interferon-gamma. J Biol Chem 1987, 262: 2528. 4. Heremans, H et al; Regulation by interferons of the local inflammatory response to bacterial lipopolysaccharide. J Immunol 1987, 138 : 4175. 5. Billiau, A et al; anti-interferon-gamma antibody protects mice against the generalized Shwartzman reaction. Eur J Immunol 1987, 17 : 1851. 6. Jacob, CO et al; in vivo treatment of (NZB X NZW) F1 lupus-like nephritis with monoclonal antibody to gamma interferon. J Exp Med 1987, 166: 798. 7. Wolfs, T et al; In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation. J immunol 2002, 168: 1286.

Other Notes

Small volumes of anti-IFN-gamma antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IFN-gamma purchase

MBS584801 is an antibody targeting IFN-gamma. Also known as IFN-gamma, Mouse, mAb F3. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for IFN-gamma. It may not necessarily be applicable to this product.

NCBI GI #
56786138
NCBI GeneID
3458
NCBI Accession #
NP_000610.2
UniProt Primary Accession #
P01579
UniProt Secondary Accession #
Q53ZV4; B5BU88
UniProt Related Accession #
P01579
GenBank Nucleotide #
NM_000619.2
NCBI Official Full Name
interferon gamma
NCBI Official Synonym Full Names
interferon gamma
NCBI Official Symbol
IFNG
NCBI Official Synonym Symbols
IFG; IFI
UniProt Protein Name
Interferon gamma
UniProt Synonym Protein Names
Immune interferon
Protein Family
Interferon gamma receptor
UniProt Gene Name
IFNG
UniProt Synonym Gene Names
IFN-gamma
NCBI Protein Information
interferon gamma

NCBI Summary for IFN-gamma

This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
Show more

UniProt Comments for IFN-gamma

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Show more

Research Articles on IFN-gamma

1. Association Between the Interferon Gamma 874 T/A Polymorphism and the Severity of Valvular Damage in Patients with Rheumatic Heart Disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IFN-gamma antibody

 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000