Rat Anti-NGF Monoclonal Antibody – Cat# MBS588027

Nerve Growth Factor (NGF) Antibody – Rat Monoclonal

Name: NGF Antibody; Monoclonal; Rat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS588027
Price: 560 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS588027

Nerve growth factor (NGF) is a small secreted protein which induces the differentiation and survival of particular target neurons. It is perhaps the prototypical growth factor; in that it is one of the first to be described. NGF is critical for the survival… More details

$560 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nerve Growth Factor (NGF), Monoclonal Antibody

Full Product Name

Nerve Growth Factor (NGF) Rat Monoclonal Antibody (NGF30)

Product Gene Name

anti-NGF antibody

Product Synonym Names

Beta-nerve growth factor; Beta-NGF; NGF

Clonality

Monoclonal

Isotype

lgG2a

Clone Number

NGF30

Host

Rat

Species Reactivity

Mouse

Form/Format

Lyophilized protein G purified in PBS pH7.4

Specificity

This antibody recognizes mouse NGF monomer protein (MW 13 kDa) by WB. It does not cross react with EGF, BSA, APO or insulin.

Preparation and Storage

Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage.
To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C).
For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

21,903 Da

3D Structure

ModBase 3D Structure for Q6YBR5

Immunogen

Polymerized NGF

Preservative

None

Applications Tested/Suitable for anti-NGF antibody

Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)

Application Notes for anti-NGF antibody

If reconstituted in 100 muL: WB: 1:200.

Product References and Citations for anti-NGF antibody

1. Debeir T-A nerve growth factor mimetic TrkA antagonist causes withdrawal of cortical cholinergic boutons in the adult rat. 2. Saragovi HU-A TrkA-selective, fast internalizing nerve growth factor-antibody complex induces trophic but not neuritogenic signals. 3. Kenigsberg RL-Two distinct monoclonal antibodies raised against mouse beta nerve growth factor.

Other Notes

Small volumes of anti-NGF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NGF purchase

MBS588027 is an antibody targeting NGF. Also known as Nerve Growth Factor (NGF) Rat Monoclonal Antibody (NGF30). Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for NGF. It may not necessarily be applicable to this product.

NCBI GI #

42409517

NCBI GeneID

58133

NCBI Accession #

NP_954680.1

UniProt Primary Accession #

Q6YBR5

UniProt Secondary Accession #

Q504K7

UniProt Related Accession #

Q6YBR5

GenBank Nucleotide #

NM_199210.1

NCBI Official Full Name

nerve growth factor

NCBI Official Synonym Full Names

nerve growth factor b (beta polypeptide)

NCBI Official Symbol

ngfb

NCBI Official Synonym Symbols

ngf; ns:zft386; xx:zft386; zgc:109730

UniProt Protein Name

Nerve growth factor

Protein Family

Beta-nerve growth factor

UniProt Gene Name

ngf

UniProt Synonym Gene Names

ngfb; NGF; zNGF

NCBI Protein Information

nerve growth factor

UniProt Comments for NGF

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NGF antibody

Products by Pathway	Pathway Diagram
ARMS-mediated Activation Pathway antibodies	ARMS-mediated Activation Pathway Diagram
Activation Of TRKA Receptors Pathway antibodies	Activation Of TRKA Receptors Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Axonal Growth Stimulation Pathway antibodies	Axonal Growth Stimulation Pathway Diagram
Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies	Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
Ceramide Signalling Pathway antibodies	Ceramide Signalling Pathway Diagram
Frs2-mediated Activation Pathway antibodies	Frs2-mediated Activation Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram

Diseases associated with anti-NGF antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>2021 publications with NGF and Nervous System Diseases
Pain Antibodies	>637 publications with NGF and Pain
Inflammation Antibodies	>616 publications with NGF and Inflammation
Nerve Degeneration Antibodies	>575 publications with NGF and Nerve Degeneration
Peripheral Nervous System Diseases Antibodies	>437 publications with NGF and Peripheral Nervous System Diseases
Drug Toxicity Antibodies	>415 publications with NGF and Drug Toxicity
Necrosis Antibodies	>415 publications with NGF and Necrosis
Hyperalgesia Antibodies	>288 publications with NGF and Hyperalgesia
Heart Diseases Antibodies	>102 publications with NGF and Heart Diseases
Movement Disorders Antibodies	>100 publications with NGF and Movement Disorders

Organs/Tissues associated with anti-NGF antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>609 publications with NGF and Muscle
Reproductive System Antibodies	>184 publications with NGF and Reproductive System
Whole Body Antibodies	>17 publications with NGF and Whole Body