Leishmania A2 Antibody – Mouse Monoclonal

Leishmania donovani is a protozoa parasite responsible for human visceral leishmaniasis. During their life cycle the parasites exist in 2 forms: as flagellated promastigote within the sandfly vector and as non-flagellated amastigote in the macrophage phagolysosomal compartment of the mammalian host. A2 protein is an amastigote-specific virulence factor that is required for Leishmania donovani parasite survival in a mammalian host.

1. Jaiswal AK-Immunological consequences of stress-related proteins-cytosolic tryparedoxin peroxidase and chaperonin TCP20--identified in splenic amastigotes. 2. Kumari S-Leishmania donovani: immunostimulatory cellular responses of membrane and soluble protein fractions of splenic amastigotes in cured patient and ham. 3. McCall LI and Matlashewski G-Localization and induction of the A2 virulence factor in Leishmania: evidence that A2 is a stress response protein. 4. Nascimento M-Identification and characterization of a protein-tyrosine phosphatase in Leishmania: Involvement in virulence. 5. Zhang WW-Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection. 6. Carvalho FA-Diagnosis of American visceral leishmaniasis in humans and dogs using the recombinant Leishmania donovani A2 antigen. 7. Zhang WW and Matlashewski G-Loss of virulence in Leishmania donovani deficient in an amastigote-specific protein, A2.

Small volumes of anti-Leishmania A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS588067 is an antibody targeting Leishmania A2. Also known as Leishmania A2 Mouse Monoclonal Antibody (C9). Host: Mouse.