CDC-5 Antibody – Mouse Monoclonal

Background: Polo-like kinases (PLKs) are evolutionarily conserved kinases essential for cell division, proliferation, and development. These kinases are characterized by the presence of a C-terminal phosphopeptide-interaction domain, the polo-box domain (PBD). Cdc5 (Msd2) is a cell cycle serine/threonine-protein kinase of Saccharomyces cerevisiae involved in mitotic exit. Recently, a novel function for Cdc5 as an important regulator of cellular ploidy has been reported.

Description: A highly specific and sensitive antibody against Cdc5 (Msd2). The antibody was raised against a Cdc5 (Msd2) recombinant protein. It contains a mixture of the clones 4F10 and 11H12.

1. Hery Ratsima, Anne-Marie Ladouceur, Mirela Pascariu, Véronique Sauvé, Zeina Salloum, Paul S. Maddox, and Damien D'Amours. Independent modulation of the kinase and polo-box activities of Cdc5 protein unravels unique roles in the maintenance of genome stability. PNAS; 108(43):E914-E923; 2011.

Small volumes of anti-Cdc-5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS588112 is an antibody targeting Cdc-5. Also known as Cdc-5 Mouse Monoclonal Antibody (4F10-11H12). Host: Mouse.