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Dopamine Beta Hydroxylase (DBH) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS588117

Studying the monoaminergic system has been of great interest and importance since dopamine, noradrenaline and adrenaline are the neurotransmitters involved in multiple physiological and pathophysiological conditions. DBH is the enzyme responsible for the… More details

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Product Overview

Product Name
Dopamine Beta Hydroxylase (DBH), Monoclonal Antibody
Full Product Name
Dopamine Beta Hydroxylase (DBH) Mouse Monoclonal Antibody (DBH41)
Product Gene Name
Product Synonym Names
Dopamine beta-monooxygenase Dopamine Beta Hydroxylase; Dopamine-hydroxylase; DBH; oxygenase; anti-Dopamine Beta Hydroxylase; anti-Dopamine-hydroxylase; anti-DBH; oxygenase
Clonality
Monoclonal
Isotype
IgG1
Clone Number
DBH41
Host
Mouse
Species Reactivity
Rat
It exhibits no cross-reactivity with either Mouse, Human, Rabbit, Guinea Pig, Cat or Bovine DBH
Form/Format
Lyophilized protein G purified in PBS pH7.4
Specificity
This antibody recognizes This antibody specifically recognizes two bands of molecular weight 70 and 75 kDa, corresponding to the soluble and membrane bound forms of the enzyme, respectively. Due to the high sensitivity of the DBH antibody, the presence of the enzyme can be immunologically detected even in areas where only scattered DBH-containing fibers are present. DBH antibody specifically stains DBH-containing neurons and fibers in the rat central nervous system (CNS).
Preparation and Storage
Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage.
To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C).
For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
69,397 Da
Preservative
None
Applications Tested/Suitable for anti-DBH antibody
Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA (EIA), Western Blot (WB)
Application Notes for anti-DBH antibody
If reconstituted in 100 muL: IHC/ICC: 1:1000.

Product References and Citations for anti-DBH antibody

1. Yen LD-Sympathetic sprouting and changes in nociceptive sensory innervation in the glabrous skin of the rat hind paw following partial peripheral nerve. 2. Ruocco I-Skin blood vessels are simultaneously innervated by sensory, sympathetic, and parasympathetic fibers. 3. Mazzoni IE-Production and immunocytochemical application of a highly sensitive and specific monoclonal antibody against rat dopamine-beta-hydroxylase.

Other Notes

Small volumes of anti-DBH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DBH purchase

MBS588117 is an antibody targeting DBH. Also known as Dopamine Beta Hydroxylase (DBH) Mouse Monoclonal Antibody (DBH41). Reactive in Rat
It exhibits no cross-reactivity with either Mouse, Human, Rabbit, Guinea Pig, Cat or Bovine DBH. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DBH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Secondary Accession #
NCBI Official Full Name
dopamine-beta-hydroxylase
UniProt Protein Name
DBH-like monooxygenase protein 2
UniProt Synonym Protein Names
Dopamine-beta-hydroxylase-like protein
UniProt Gene Name
Moxd2
UniProt Synonym Gene Names
Dbhl; Dbhl1

UniProt Comments for DBH

MOXD2: Belongs to the copper type II ascorbate-dependent monooxygenase family.

Protein type: Membrane protein, integral; EC 1.14.17.-; Oxidoreductase

Cellular Component: membrane; integral to membrane

Molecular Function: copper ion binding; metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen; oxidoreductase activity; catalytic activity; monooxygenase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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