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TAU Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS588236

Tauopathies are a group of diverse dementias and movement disorders which have a common pathological feature in that they all display the presence of intracellular accumulation of abnormal filaments of tau protein. Furthermore, these accumulated tau proteins… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Product Name
Tau, Polyclonal Antibody
Full Product Name
Phospho-Tau (ser 208/210) Rabbit Polyclonal Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Lyophilized immunogen affinity purified in PBS pH7.4
Specificity
The antibody recognizes the human Phospho-Tau protein peptide at the Serines 208 and 210 (Ser 208/210) phosphorylation site. (MW 48-67 kDa)
Preparation and Storage
Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage.
To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C).
For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
Immunogen
Peptide phosphorylated at Ser 208 and Ser 210
Target
Phospho-Tau (ser 208/210)
Applications Tested/Suitable for anti-Tau antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-Tau antibody
If reconstituted with deionized water in 50 muL:
WB: 1:10000
IHC: 1:1000.Optimal dilutions have to be determined by the user.

Immunohistochemistry (IHC) of anti-Tau antibody

Immuohistochemistry analysis of a competition assay demonstrating the specificity of the anti-Tau (Ser 208/210) antibody.
Rabbit Anti-TAU Polyclonal Antibody – Cat# MBS588236

Western Blot (WB) of anti-Tau antibody

Western blot detection of insoluble phospho-Tau protein using the anti-Tau (Ser 208/210) antibody in samples isolated from patients with a neurodegenerative disease (Amyotropic lateral sclerosis, ALSci or Alzheimer's disease, AD).
Rabbit Anti-TAU Polyclonal Antibody, Western Blot (WB) – Cat# MBS588236

Product References and Citations for anti-Tau antibody

1. Gohar M-Tau phosphorylation at threonine-175 leads to fibril formation and enhanced cell death: implications for amyotrophic lateral sclerosis with cogniti. 2. Strong MJ-Tau protein hyperphosphorylation in sporadic ALS with cognitive impairment.

Other Notes

Small volumes of anti-Tau antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tau purchase

MBS588236 is an antibody targeting Tau. Also known as Phospho-Tau (ser 208/210) Rabbit Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Tau. It may not necessarily be applicable to this product.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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