Chicken TDGF1 ELISA Kit – Cat# MBS005896

Teratocarcinoma Derived Growth Factor 1 (TDGF1) ELISA Kit for Chicken

Name: Chicken TDGF1 ELISA Kit; Teratocarcinoma Derived Growth Factor 1; MyBioSource
Brand: MyBioSource
SKU: MBS005896
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS005896

MBS005896 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Teratocarcinoma Derived Growth Factor 1 (TDGF1) ELISA Kit target analytes in biological samples. The concentration… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Teratocarcinoma Derived Growth Factor 1 (TDGF1), ELISA Kit

Full Product Name

Chicken Teratocarcinoma Derived Growth Factor 1 ELISA Kit

Product Gene Name

TDGF1 elisa kit

Species Reactivity

Chicken

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

21,169 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (46616045..46623953). Location: 3p21.31

OMIM

187395

3D Structure

ModBase 3D Structure for P13385

Other Notes

Small volumes of TDGF1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TDGF1. It may not necessarily be applicable to this product.

NCBI GI #

292494883

NCBI GeneID

6997

NCBI Accession #

NP_001167607.1

UniProt Primary Accession #

P13385

UniProt Secondary Accession #

Q8TCC1

UniProt Related Accession #

P13385

GenBank Nucleotide #

NM_001174136.1

NCBI Official Full Name

teratocarcinoma-derived growth factor 1 isoform 2

NCBI Official Synonym Full Names

teratocarcinoma-derived growth factor 1

NCBI Official Symbol

TDGF1

NCBI Official Synonym Symbols

CR; CRGF; CRIPTO

UniProt Protein Name

Teratocarcinoma-derived growth factor 1

UniProt Synonym Protein Names

Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1

Protein Family

Teratocarcinoma-derived growth factor

UniProt Gene Name

TDGF1

UniProt Synonym Gene Names

CRIPTO; CRGF

UniProt Entry Name

TDGF1_HUMAN

NCBI Protein Information

teratocarcinoma-derived growth factor 1; cripto-1 growth factor; epidermal growth factor-like cripto protein CR1

NCBI Summary for TDGF1

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

UniProt Comments for TDGF1

TDGF1: Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Interacts with the activin type-1 receptor ACVR1B. Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. Expressed in breast and lung.

Protein type: Motility/polarity/chemotaxis; Cell adhesion; Cell cycle regulation; Membrane protein, peripheral; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: extrinsic to plasma membrane; Golgi apparatus; extracellular space; cell surface; perinuclear region of cytoplasm; apical plasma membrane; plasma membrane; nucleus; lipid raft

Molecular Function: protein binding; growth factor activity; receptor binding

Biological Process: activation of MAPK activity; somatic stem cell maintenance; heart development; regulation of signal transduction; gastrulation; Wnt receptor signaling pathway through beta-catenin; cardiac muscle cell differentiation; BMP signaling pathway; positive regulation of fibroblast proliferation; mammary gland development; determination of anterior/posterior axis, embryo; positive regulation of cell proliferation; cell differentiation; vasculogenesis; positive regulation of cell-matrix adhesion; epidermal growth factor receptor signaling pathway; in utero embryonic development; morphogenesis of a branching structure; positive regulation of peptidyl-tyrosine phosphorylation; embryonic development; peptidyl-serine phosphorylation; cell migration during sprouting angiogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of cell migration; negative regulation of apoptosis

Research Articles on TDGF1

1. Cross-talk between Cripto-1 and the Wnt/beta-catenin signaling pathway might play a role in mammary transformation leading to a more aggressive behavior of mammary cancer cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TDGF1 elisa kit

Reference Product	PubMed Publications
NODAL elisa kit	>80 publications with TDGF1 and NODAL
ACVR1B elisa kit	>18 publications with TDGF1 and ACVR1B
ACVR2A elisa kit	>3 publications with TDGF1 and ACVR2A
ACVR1C elisa kit	>3 publications with TDGF1 and ACVR1C
ACVR2B elisa kit	>1 publications with TDGF1 and ACVR2B

Pathways associated with TDGF1 elisa kit

Products by Pathway	Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Glypican 1 Network Pathway antibodies	Glypican 1 Network Pathway Diagram
Regulation Of Signaling By NODAL Pathway antibodies	Regulation Of Signaling By NODAL Pathway Diagram
Signaling By NODAL Pathway antibodies	Signaling By NODAL Pathway Diagram

Diseases associated with TDGF1 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>120 publications with TDGF1 and Neoplasms
Skin Diseases Antibodies	>31 publications with TDGF1 and Skin Diseases
Gastrointestinal Diseases Antibodies	>29 publications with TDGF1 and Gastrointestinal Diseases
Intestinal Neoplasms Antibodies	>25 publications with TDGF1 and Intestinal Neoplasms
Adenocarcinoma Antibodies	>19 publications with TDGF1 and Adenocarcinoma
Neoplasms, Experimental Antibodies	>12 publications with TDGF1 and Neoplasms, Experimental
Nervous System Diseases Antibodies	>11 publications with TDGF1 and Nervous System Diseases
Holoprosencephaly Antibodies	>9 publications with TDGF1 and Holoprosencephaly
Craniofacial Abnormalities Antibodies	>7 publications with TDGF1 and Craniofacial Abnormalities
Nervous System Malformations Antibodies	>7 publications with TDGF1 and Nervous System Malformations

Organs/Tissues associated with TDGF1 elisa kit

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>57 publications with TDGF1 and Embryonic Tissue
Muscle Antibodies	>22 publications with TDGF1 and Muscle
Brain Antibodies	>12 publications with TDGF1 and Brain
Liver Antibodies	>11 publications with TDGF1 and Liver
Testis Antibodies	>7 publications with TDGF1 and Testis
Uterus Antibodies	>6 publications with TDGF1 and Uterus
Kidney Antibodies	>4 publications with TDGF1 and Kidney
Prostate Antibodies	>4 publications with TDGF1 and Prostate
Intestine Antibodies	>4 publications with TDGF1 and Intestine
Spleen Antibodies	>3 publications with TDGF1 and Spleen