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MCP-3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS592023

Mouse monoclonal antibody to human macrophage/monocyte chemotactic protein-3 (MCP-3), Protein G affinity purified More details

$405 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MCP-3, Monoclonal Antibody
Full Product Name
mAb anti-human MCP-3
Product Gene Name
anti-MCP-3 antibody
Product Synonym Names
Macrophage/Monocyte Chemotactic Protein (MCP-3) ; Mouse monoclonal antibody to human macrophage/monocyte chemotactic protein-3 (MCP-3)
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
1015
Host
Mouse
Species Reactivity
Human. Other species not tested
Does not show any cross reaction with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, SAA and EGF.
Form/Format
Lyophilized from a solution in 0.01M PBS, pH 7.2.
Purity/Purification
Protein G affinity purified
Specificity
Reactive with natural and recombinant human Macrophage/Monocyte Chemotactic Protein (MCP-3)
Preparation and Storage
Store at -20 degree C
Molecular Weight
11,200 Da
OMIM
158106
3D Structure
ModBase 3D Structure for P80098
Target Protein
Human MCP-3
Immunogen
Recombinant human MCP-3 (M.W. 8.5kDa containing 76 amino acids residues)
Myeloma
Sp2/0-Ag14
Light Chain
Kappa
Reconstitution
Double distillated water is recommended to reconstitute the antibody.
Research Area
Cytokine, chemotaxis.

Product Categories/Family for anti-MCP-3 antibody

Primary Antibodies; Monoclonal Antibodies to Human Cytokines and Growth Factors
ISO Certification
Manufactured in an ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-MCP-3 antibody
Western Blot (WB)
Application Notes for anti-MCP-3 antibody
Western Blot: This antibody, when used at concentration of 0.5-2mug/mL will allow visualization of 0.1mug/lane of human MCP-3.

Other Notes

Small volumes of anti-MCP-3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MCP-3 purchase

MBS592023 is an antibody targeting MCP-3. Also known as mAb anti-human MCP-3. Reactive in Human. Other species not tested
Does not show any cross reaction with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, SAA and EGF.. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MCP-3. It may not necessarily be applicable to this product.

NCBI GI #
313708
NCBI Accession #
CAA51055.1
UniProt Primary Accession #
P80098
UniProt Secondary Accession #
Q569J6
NCBI Official Full Name
monocyte chemotactic protein-3
UniProt Protein Name
C-C motif chemokine 7
UniProt Synonym Protein Names
Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; NC28; Small-inducible cytokine A7
Protein Family
Mastin
UniProt Gene Name
CCL7
UniProt Entry Name
CCL7_HUMAN

UniProt Comments for MCP-3

CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space; extracellular region

Molecular Function: heparin binding; CCR1 chemokine receptor binding; CCR2 chemokine receptor binding; chemokine activity

Biological Process: cellular calcium ion homeostasis; monocyte chemotaxis; regulation of cell shape; cell-cell signaling; eosinophil chemotaxis; response to gamma radiation; cytoskeleton organization and biogenesis; immune response; chemotaxis; inflammatory response; signal transduction; positive regulation of cell migration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MCP-3 antibody

 Reference Product  PubMed Publications
 CCL2 antibody  >261 publications with MCP-3 and CCL2
 CCL5 antibody  >124 publications with MCP-3 and CCL5
 CCR2 antibody  >92 publications with MCP-3 and CCR2
 CCL11 antibody  >71 publications with MCP-3 and CCL11
 CCR1 antibody  >45 publications with MCP-3 and CCR1
 CCR3 antibody  >43 publications with MCP-3 and CCR3
 CCR5 antibody  >37 publications with MCP-3 and CCR5
 CCL17 antibody  >24 publications with MCP-3 and CCL17
 CXCR3 antibody  >10 publications with MCP-3 and CXCR3
 CCR10 antibody  >3 publications with MCP-3 and CCR10

Diseases associated with anti-MCP-3 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >191 publications with MCP-3 and Inflammation
 Respiratory Tract Diseases Antibodies  >65 publications with MCP-3 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >57 publications with MCP-3 and Lung Diseases
 Hypersensitivity Antibodies  >53 publications with MCP-3 and Hypersensitivity
 Necrosis Antibodies  >52 publications with MCP-3 and Necrosis
 Disease Models, Animal Antibodies  >49 publications with MCP-3 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >25 publications with MCP-3 and Cardiovascular Diseases
 Fibrosis Antibodies  >23 publications with MCP-3 and Fibrosis
 Heart Diseases Antibodies  >12 publications with MCP-3 and Heart Diseases
 Carcinoma Antibodies  >10 publications with MCP-3 and Carcinoma

Organs/Tissues associated with anti-MCP-3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >280 publications with MCP-3 and Blood
 Lung Antibodies  >70 publications with MCP-3 and Lung
 Skin Antibodies  >35 publications with MCP-3 and Skin
 Intestine Antibodies  >14 publications with MCP-3 and Intestine
 Uterus Antibodies  >10 publications with MCP-3 and Uterus
 Placenta Antibodies  >4 publications with MCP-3 and Placenta
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