Mouse Anti-TGF-beta Monoclonal Antibody – Cat# MBS592144

TGF-beta Antibody – Mouse Monoclonal

Name: TGF-beta Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS592144
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS592144

Mouse monoclonal antibody to human Transforming Growth Factor beta (TGF-β (beta)), Protein G affinity purified More details

$405 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TGF-beta, Monoclonal Antibody

Full Product Name

mAb anti-Human TGF-beta

Product Gene Name

anti-TGF-beta antibody

Product Synonym Names

Transforming Growth Factor Beta (TGF-beta); Transforming Growth Factor Beta (TGF-b); Mouse monoclonal antibody to human Transforming Growth Factor beta (TGF-beta)

Clonality

Monoclonal

Isotype

IgG1, k

Clone Number

TB21

Host

Mouse

Species Reactivity

Human. Other species not tested

Form/Format

Lyophilized from a solution in 0.01M PBS, pH 7.0

Purity/Purification

Protein G affinity purified

Specificity

Western blotting demonstrated that this antibody reacts with the dimeric (25 kDa) and monomeric (12.5 kDa.) forms of TGF-beta under both non-reducing and reducing conditions respectively. This antibody recognizes both human platelet-derived and recombinant TGF-beta in ELISA.
Transforming Growth Factor Beta (TGF-beta)

Preparation and Storage

Store at -20 degree C

Target Protein

Human TGF-beta

Immunogen

TGF-beta from human platelets

Myeloma

Sp2/0-Ag14

Light Chain

Kappa

Reconstitution

Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Research Area

Growth Factors and Their Receptors, Angiogenesis

Product Categories/Family for anti-TGF-beta antibody

Primary Antibodies; Monoclonal Antibodies to Human Cytokines and Growth Factors

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-TGF-beta antibody

NT, Immunohistochemistry (IHC), Western Blot (WB)

Application Notes for anti-TGF-beta antibody

Neutralizing: This antibody neutralizes TGF-beta activity in vitro and in vivo. In an inhibition assay of CCL/64 cell growth and in a NRK-49F colony forming assay, the antibody neutralized TGF-beta bioactivities. The effect of micro-injection of this antibody into one blastomere of two cell stage Xenopus embryos indicated that it was also able to neutralize the bioactivity of TGF-beta in vivo.
IHC: This antibody has been used to demonstrate TGF-beta in ovine ovarian tissue and human breast carcinoma at a dilution of 1:1000. As a consequence of the intense staining of the erythrocytes, it is possible to locate a single cell within the ovarian stroma, making it useful in locating very fine capillary networks within tissue.
Western Blot: This antibody when used at concentration of 5-20ng/mL will allow visualization of 100ng/lane of TGF-beta.

Product References and Citations for anti-TGF-beta antibody

Crawford, S. E. Thrombospondin-1 is a major activator of TGF-beta1 in vivo. Cell 93:1159-1170 (1998)
Biological characterization of a monoclonal antibody TB21 against human transforming growth factor-beta 1. Acta Biologiae Experimentalis Sinica Vol. 26, No. 2 June (1993).

Other Notes

Small volumes of anti-TGF-beta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TGF-beta purchase

MBS592144 is an antibody targeting TGF-beta. Also known as mAb anti-Human TGF-beta. Reactive in Human. Other species not tested. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TGF-beta. It may not necessarily be applicable to this product.

Protein Family

TGF-beta-activated kinase 1 and MAP3K7-binding protein

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.