Transient Receptor Potential Cation Channel V1 (TRPV1) Antibody – Rabbit Polyclonal

TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, misc.; Channel, cation

Cellular Component: postsynaptic membrane; neuron projection; cell projection; cell soma; membrane; dendrite; integral to membrane; plasma membrane; synapse; cytosol; cell junction; intrinsic to plasma membrane; external side of plasma membrane

Molecular Function: identical protein binding; excitatory extracellular ligand-gated ion channel activity; calcium channel activity; nucleotide binding; ion channel activity; phosphoprotein binding; ligand-gated ion channel activity; calmodulin binding; chloride channel regulator activity; transmembrane receptor activity; cation transmembrane transporter activity; calcium-release channel activity; cation channel activity; ATP binding

Biological Process: urinary bladder smooth muscle contraction; diet induced thermogenesis; catagen; positive regulation of nitric oxide biosynthetic process; positive regulation of apoptosis; microglial cell activation; response to pain; sensory perception of mechanical stimulus; thermoception; thermoregulation; sensory perception of pain; signal transduction; fever; behavioral response to pain; elevation of cytosolic calcium ion concentration; transport; calcium ion transport; transmembrane transport; cation transport; peptide secretion; detection of chemical stimulus involved in sensory perception of pain; response to organic nitrogen; glutamate secretion; smooth muscle contraction involved in micturition; response to heat; ion transport; lipid metabolic process; response to pH