Thr181 Phosphorylated Tau Antibody – Mouse Monoclonal

Description: Mouse monoclonal antibody against Thr181 phosphorylated Tau protein

background: Tau is a highly soluble microtubule associated protein found in high concentration in neuron of central nervous system. The main function of the protein is stabilizing the microtubule in nerve fibre (axon). There are six tau isoforms which are formed by alternate splicing. Hyperphosphorylation of Tau protein results in aggregation and formation of neurofibrillary tangles, which is significantly associated with cognitive impairment in Alzheimer's disease. Tau Thr181 phosphorylation has been used as a biomarker for the differentiation of Alzheimer's disease and other primary dementia such as dementia with Lewy bodies.

Small volumes of anti-Thr181 phosphorylated Tau antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS592364 is an antibody targeting Thr181 phosphorylated Tau. Also known as mAb anti-human Thr181 phosphorylated Tau. Reactive in Human, Mouse. Host: Mouse.