Cardiac Fatty Acid Binding Recombinant Protein

Heart-fatty acid binding protein (h-FABP) is a sensitive biomarker detected in the blood within 1 to 3 hours of chest pain for myocardial infarction. H-FABP is 20 times more specific to cardiac muscle than myoglobin. H-FABP is used to be tested with troponin to identify myocardial infarction and acute coronary syndrome with chest pain. Due to the high concentration of H-FABP in myocardium, H-FABP measured with troponin shows increased sensitivity of 20.6% over troponin at 3-6 hours after chest pain. It rapidly releases into plasma after 60 minutes of myocardial injury, clinical study showed that measuring H-FABP in combination with troponin increased the accuracy and specifity to exclude the patients without myocardial infarction at 3-6 hours early time after chest pain. Full length h-FABP was expressed and purified from E Coli and a 6 x his tag is linked to its C- terminus, it migrated at 17kDa on SDS-PAGE. This recombinant protein is used as a tool in the quality control for h-FABP test product to quantitate the sensitivity of h-FABP test product or used as positive control.

Small volumes of Cardiac fatty acid binding recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS596043 is a recombinant protein targeting Cardiac fatty acid binding. Also known as Recombinant human cardiac fatty acid binding protein. Host: E Coli.