Cov-MERS Spike-RBD (CoV-MERS) Recombinant Protein

Since April 2012, cases of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have been identified in middle east and other countries. This virus is also classified into coronaviruse family, causing severe illnesses with over 40% mortality.
Like other coronaviruses, large surface spike glycoprotein is one important structural protein of thisvirus, it is located over the virion surface to bind to and entry into the target cell. Sipke protein has two domains, S1 and S2, S1 domain is responsible for cellular tropism and interaction with target cell, while S2 domain responsible for membrane fusion. C terminus of S1 contains a receptor binding domain with potential for vaccine development and identification.A peptide from amino acids 367 to 606 spike protein S1 is expressed and purified from E Coli, a 6 x His tag is attached to its C terminus.

Small volumes of CoV-MERS recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS596077 is a recombinant protein targeting CoV-MERS. Also known as CoV-MERS spike-RBD. Host: E Coli.