Rabbit Anti-TMED1 Polyclonal Antibody – Cat# MBS6000245

TMED1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the TMED1 antibody detected the TMED1 protein (arrow).

TMED1 Antibody – Rabbit Polyclonal

Name: TMED1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6000245
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6000245

The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1). This protein lacks any similarity to other interleukin 1 ligands. The functional significance of its interaction with IL1RL1 is not known. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TMED1, Polyclonal Antibody

Full Product Name

TMED1, ID (TMED1, IL1RL1L, IL1RL1LG, Transmembrane emp24 domain-containing protein 1, Interleukin-1 receptor-like 1 ligand, Putative T1/ST2 receptor-binding protein, p24 family protein gamma-1)

Product Gene Name

anti-TMED1 antibody

Product Synonym Names

Anti -TMED1, ID (TMED1, IL1RL1L, IL1RL1LG, Transmembrane emp24 domain-containing protein 1, Interleukin-1 receptor-like 1 ligand, Putative T1/ST2 receptor-binding protein, p24 family protein gamma-1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

25,206 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (10942743..10946983, complement). Location: 19p13.2

OMIM

605395

3D Structure

ModBase 3D Structure for Q13445

Immunogen

TMED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the Central region of human TMED1.

Product Categories/Family for anti-TMED1 antibody

Antibodies; Abs to Transmembrane Proteins

Applications Tested/Suitable for anti-TMED1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-TMED1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-TMED1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMED1 purchase

MBS6000245 is an antibody targeting TMED1. Also known as TMED1, ID (TMED1, IL1RL1L, IL1RL1LG, Transmembrane emp24 domain-containing protein 1, Interleukin-1 receptor-like 1 ligand, Putative T1/ST2 receptor-binding protein, p24 family protein gamma-1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TMED1. It may not necessarily be applicable to this product.

NCBI GI #

5803040

NCBI GeneID

11018

NCBI Accession #

NP_006849.1

UniProt Primary Accession #

Q13445

UniProt Related Accession #

Q13445

GenBank Nucleotide #

NM_006858.3

NCBI Official Full Name

transmembrane emp24 domain-containing protein 1

NCBI Official Synonym Full Names

transmembrane emp24 protein transport domain containing 1

NCBI Official Symbol

TMED1

NCBI Official Synonym Symbols

Tp24; Il1rl1l; IL1RL1LG

UniProt Protein Name

Transmembrane emp24 domain-containing protein 1

UniProt Synonym Protein Names

Interleukin-1 receptor-like 1 ligand; Putative T1/ST2 receptor-binding protein; p24 family protein gamma-1

Protein Family

Transmembrane emp24 domain-containing protein

UniProt Gene Name

TMED1

UniProt Synonym Gene Names

IL1RL1L; IL1RL1LG; Tp24; p24gamma1

UniProt Entry Name

TMED1_HUMAN

NCBI Protein Information

transmembrane emp24 domain-containing protein 1; IL1RL1-binding protein; p24 family protein gamma-1; interleukin 1 receptor-like 1 ligand; putative T1/ST2 receptor-binding protein

NCBI Summary for TMED1

This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

UniProt Comments for TMED1

TMED1: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Belongs to the EMP24/GP25L family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; endoplasmic reticulum; plasma membrane; ER-Golgi intermediate compartment; integral to membrane

Molecular Function: protein binding; receptor binding

Biological Process: protein transport; cell-cell signaling; signal transduction

Research Articles on TMED1

1. The GOLD domain-containing protein TMED1 is involved in interleukin-33 signaling

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TMED1 antibody

Reference Product	PubMed Publications
IL1RL1 antibody	>1 publications with TMED1 and IL1RL1

Organs/Tissues associated with anti-TMED1 antibody

Organ/Tissue Name	Pubmed Publications
Spleen Antibodies	>1 publications with TMED1 and Spleen
Bone Antibodies	>1 publications with TMED1 and Bone