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DLGAP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6000246

May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. More details

$785 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DLGAP2, Polyclonal Antibody
Full Product Name
DLGAP2, ID (Disks Large-associated Protein 2, DAP-2, PSD-95/SAP90-binding Protein 2, SAP90/PSD-95-associated Protein 2, SAPAP2, DAP2)
Product Gene Name
Product Synonym Names
Anti -DLGAP2, ID (Disks Large-associated Protein 2, DAP-2, PSD-95/SAP90-binding Protein 2, SAP90/PSD-95-associated Protein 2, SAPAP2, DAP2)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human DLGAP2. Species sequence homology: mouse and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
117,620 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (877021..1656642). Location: 8p23
OMIM
605438
3D Structure
ModBase 3D Structure for Q9P1A6
Immunogen
Synthetic peptide corresponding to 16aa from near the center of human SAPAP2.

Product Categories/Family for anti-DLGAP2 antibody

Applications Tested/Suitable for anti-DLGAP2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-DLGAP2 antibody
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 0.5-1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Immunohistochemistry (IHC) of anti-DLGAP2 antibody

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-DLGAP2 Polyclonal Antibody – Cat# MBS6000246

Testing Data of anti-DLGAP2 antibody

Human Colon, Submucosal Plexus
Rabbit Anti-DLGAP2 Polyclonal Antibody, Testing Data – Cat# MBS6000246

Western Blot (WB) of anti-DLGAP2 antibody

Western blot analysis of DLGAP2 in L1210 cell lysate with DLGAP2 antibody at (A) 0.5 and (B) 1ug/ml.
Rabbit Anti-DLGAP2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6000246

Other Notes

Small volumes of anti-DLGAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLGAP2 purchase

MBS6000246 is an antibody targeting DLGAP2. Also known as DLGAP2, ID (Disks Large-associated Protein 2, DAP-2, PSD-95/SAP90-binding Protein 2, SAP90/PSD-95-associated Protein 2, SAPAP2, DAP2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DLGAP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
disks large-associated protein 2 isoform 2
NCBI Official Synonym Full Names
discs, large (Drosophila) homolog-associated protein 2
NCBI Official Symbol
DLGAP2
NCBI Official Synonym Symbols
DAP2; SAPAP2
UniProt Protein Name
Disks large-associated protein 2
UniProt Synonym Protein Names
PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2
UniProt Gene Name
DLGAP2
UniProt Synonym Gene Names
DAP2; DAP-2; SAPAP2
UniProt Entry Name
DLGP2_HUMAN
NCBI Protein Information
disks large-associated protein 2; PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2

NCBI Summary for DLGAP2

The product of this gene is a membrane-associated guanylate kinase. The encoded protein may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Mar 2013]
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UniProt Comments for DLGAP2

SAPAP2: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, other

Chromosomal Location of Human Ortholog: 8p23

Cellular Component: postsynaptic membrane; postsynaptic density; neurofilament; cell junction

Molecular Function: protein binding

Biological Process: nerve-nerve synaptic transmission
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DLGAP2 antibody

Organs/Tissues associated with anti-DLGAP2 antibody

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