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CORO7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6000289

Coronins, such as CORO7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins. CORO7 plays a role in Golgi complex morphology and function (Rybakin et al., 2004, 2006 [PubMed 15327992] [PubMed 16905771]). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CORO7, Polyclonal Antibody
Full Product Name
CORO7, NT (CORO7, Coronin-7, 70kD WD repeat tumor rejection antigen homolog)
Product Gene Name
Product Synonym Names
Anti -CORO7, NT (CORO7, Coronin-7, 70kD WD repeat tumor rejection antigen homolog)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
99,252 Da
Chromosome Location
Chromosome: 25; AC_000182.1 (3508278..3561398, complement). Location: chromosome: 25
3D Structure
ModBase 3D Structure for Q0V8F1
Immunogen
CORO7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-206 amino acids from the N-terminal region of human CORO7.
Applications Tested/Suitable for anti-CORO7 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CORO7 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100

Western Blot (WB) of anti-CORO7 antibody

CORO7 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CORO7 antibody detected the CORO7 protein (arrow).
Rabbit Anti-CORO7 Polyclonal Antibody – Cat# MBS6000289

Immunohistochemistry (IHC) of anti-CORO7 antibody

CORO7 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CORO7 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-CORO7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6000289

Other Notes

Small volumes of anti-CORO7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CORO7 purchase

MBS6000289 is an antibody targeting CORO7. Also known as CORO7, NT (CORO7, Coronin-7, 70kD WD repeat tumor rejection antigen homolog). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CORO7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
coronin-7
NCBI Official Synonym Full Names
coronin 7<
NCBI Official Symbol
CORO7
UniProt Protein Name
Coronin-7
Protein Family
UniProt Gene Name
CORO7
UniProt Synonym Gene Names
Crn7
UniProt Entry Name
CORO7_BOVIN
NCBI Protein Information
coronin-7; crn7

UniProt Comments for CORO7

Function: May play a role in the maintenance of the Golgi apparatus morphology and in the protein export from the Golgi

By similarity.

Subunit structure: Interacted with clathrin adapter AP1 complex. This interaction takes place at Golgi membranes and not AP1-positive endosomal membranes

By similarity.

Subcellular location: Cytoplasm › cytosol

By similarity. Golgi apparatus membrane

By similarity. Cytoplasmic vesicle

By similarity. Note: Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments

By similarity.

Post-translational modification: The membrane-associated form is phosphorylated on tyrosine residues

By similarity.

Sequence similarities: Belongs to the WD repeat coronin family.Contains 8 WD repeats.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CORO7 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with CORO7 and Brain
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