• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

XRCC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6000760

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
XRCC2, Polyclonal Antibody
Full Product Name
XRCC2, NT (XRCC2, DNA repair protein XRCC2, X-ray repair cross-complementing protein 2)
Product Gene Name
anti-XRCC2 antibody
Product Synonym Names
Anti -XRCC2, NT (XRCC2, DNA repair protein XRCC2, X-ray repair cross-complementing protein 2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
31,956 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (152343583..152373250, complement). Location: 7q36.1
OMIM
600375
3D Structure
ModBase 3D Structure for O43543
Immunogen
XRCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human XRCC2.

Product Categories/Family for anti-XRCC2 antibody

Antibodies; Abs to DNA Replication; Repair
Applications Tested/Suitable for anti-XRCC2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-XRCC2 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-XRCC2 antibody

XRCC2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the XRCC2 antibody detected the XRCC2 protein (arrow).
Rabbit Anti-XRCC2 Polyclonal Antibody – Cat# MBS6000760

Other Notes

Small volumes of anti-XRCC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XRCC2 purchase

MBS6000760 is an antibody targeting XRCC2. Also known as XRCC2, NT (XRCC2, DNA repair protein XRCC2, X-ray repair cross-complementing protein 2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for XRCC2. It may not necessarily be applicable to this product.

NCBI GI #
3288461
NCBI GeneID
7516
NCBI Accession #
CAA70065.1
UniProt Primary Accession #
O43543
UniProt Secondary Accession #
B2R925
UniProt Related Accession #
O43543
NCBI Official Full Name
XRCC2
NCBI Official Synonym Full Names
X-ray repair complementing defective repair in Chinese hamster cells 2
NCBI Official Symbol
XRCC2
UniProt Protein Name
DNA repair protein XRCC2
UniProt Synonym Protein Names
X-ray repair cross-complementing protein 2
Protein Family
DNA repair protein
UniProt Gene Name
XRCC2
UniProt Entry Name
XRCC2_HUMAN
NCBI Protein Information
DNA repair protein XRCC2; X-ray repair cross-complementing protein 2

UniProt Comments for XRCC2

XRCC2: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Belongs to the RecA family. RAD51 subfamily.

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: centrosome; cytoplasm; replication fork

Molecular Function: DNA-dependent ATPase activity; protein binding; four-way junction DNA binding; ATP binding

Biological Process: meiosis; positive regulation of neurogenesis; somitogenesis; in utero embryonic development; multicellular organism growth; strand invasion; DNA repair; double-strand break repair via homologous recombination; centrosome organization and biogenesis; response to gamma radiation; negative regulation of neuron apoptosis; mitotic cell cycle; response to X-ray
Show more

Research Articles on XRCC2

1. Our data do not confirm an association between XRCC2 variants and breast cancer risk, although a relative risk smaller than two could not be excluded.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-XRCC2 antibody

 Reference Product  PubMed Publications
 XRCC3 antibody  >129 publications with XRCC2 and XRCC3
 RAD51C antibody  >56 publications with XRCC2 and RAD51C
 BRCA2 antibody  >30 publications with XRCC2 and BRCA2
 XRCC1 antibody  >29 publications with XRCC2 and XRCC1
 RAD51L3 antibody  >21 publications with XRCC2 and RAD51L3
 RAD52 antibody  >20 publications with XRCC2 and RAD52
 XRCC4 antibody  >13 publications with XRCC2 and XRCC4
 RAD51L1 antibody  >8 publications with XRCC2 and RAD51L1
 BLM antibody  >3 publications with XRCC2 and BLM

Pathways associated with anti-XRCC2 antibody

 Products by Pathway  Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram

Diseases associated with anti-XRCC2 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >83 publications with XRCC2 and Neoplasms
 Breast Neoplasms Antibodies  >31 publications with XRCC2 and Breast Neoplasms
 Death Antibodies  >14 publications with XRCC2 and Death
 Adenocarcinoma Antibodies  >12 publications with XRCC2 and Adenocarcinoma
 Anemia Antibodies  >8 publications with XRCC2 and Anemia
 Ovarian Diseases Antibodies  >8 publications with XRCC2 and Ovarian Diseases
 Lung Neoplasms Antibodies  >7 publications with XRCC2 and Lung Neoplasms
 Skin Neoplasms Antibodies  >4 publications with XRCC2 and Skin Neoplasms
 Cell Transformation, Neoplastic Antibodies  >4 publications with XRCC2 and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >4 publications with XRCC2 and Neoplasms, Experimental

Organs/Tissues associated with anti-XRCC2 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >5 publications with XRCC2 and Testis
 Brain Antibodies  >4 publications with XRCC2 and Brain
 Mouth Antibodies  >3 publications with XRCC2 and Mouth
 Embryonic Tissue Antibodies  >3 publications with XRCC2 and Embryonic Tissue
 Lymph Node Antibodies  >1 publications with XRCC2 and Lymph Node
 Liver Antibodies  >1 publications with XRCC2 and Liver
 Mammary Gland Antibodies  >1 publications with XRCC2 and Mammary Gland
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000