Neurofilament L, 68kD Antibody – Rabbit Polyclonal

Neurofilaments are the intermediate filaments found in neuronal cells. They are composed of a combination of subunit proteins which typically includes the neurofilment triplet proteins, NF-L (68kD), NF-M (160kD), and NF-H (200kD). Neurofilaments may also include peripherin, alpha-internexin (NF66), nestin, and vimentin. Antibodies to the various neurofilament subunits are useful biomarkers; the filaments are abundant and biochemically stable. The expression of neurofilament proteins varies during neuronal development and differentiation and between between neuronal cell subtypes, and altered in pathological states. Accumulation of neurofilaments is observed the progression of numerous neurological diseases.

Small volumes of anti-Neurofilament L, 68kD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS6000777 is an antibody targeting Neurofilament L, 68kD. Also known as Neurofilament L, 68kD (NF-L, NFL, 68kD Neurofilament Protein, CMT1F, CMT2E, NEFL, Neurofilament Light Polypeptide 68kD, NF68, Neurofilament Triplet L Protein). Reactive in Human. Host: Rabbit.