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C5H12orf5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6000931

This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and… More details

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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TIGAR (C5H12orf5), Polyclonal Antibody
Full Product Name
TIGAR, NT (TIGAR, C12orf5, Fructose-2,6-bisphosphatase TIGAR, TP53-induced glycolysis and apoptosis regulator)
Product Gene Name
Product Synonym Names
Anti -TIGAR, NT (TIGAR, C12orf5, Fructose-2,6-bisphosphatase TIGAR, TP53-induced glycolysis and apoptosis regulator)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
29,467 Da
Chromosome Location
Chromosome: 5; AC_000162.1 (106222890..106238040, complement). Location: chromosome: 5
3D Structure
ModBase 3D Structure for Q1JQA7
Immunogen
TIGAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TIGAR.
Applications Tested/Suitable for anti-C5H12orf5 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-C5H12orf5 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-C5H12orf5 antibody

TIGAR Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TIGAR antibody detected the TIGAR protein (arrow).
Rabbit Anti-C5H12orf5 Polyclonal Antibody – Cat# MBS6000931

Other Notes

Small volumes of anti-C5H12orf5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C5H12orf5 purchase

MBS6000931 is an antibody targeting C5H12orf5. Also known as TIGAR, NT (TIGAR, C12orf5, Fructose-2,6-bisphosphatase TIGAR, TP53-induced glycolysis and apoptosis regulator). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for C5H12orf5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
TPA: probable fructose-2,6-bisphosphatase TIGAR
NCBI Official Symbol
C5H12orf5
NCBI Official Synonym Symbols
TIGAR
UniProt Protein Name
Fructose-2,6-bisphosphatase TIGAR
UniProt Synonym Protein Names
TP53-induced glycolysis and apoptosis regulator
UniProt Gene Name
TIGAR
UniProt Entry Name
TIGAR_BOVIN
NCBI Protein Information
fructose-2,6-bisphosphatase TIGAR; probable fructose-2,6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator

UniProt Comments for C5H12orf5

Function: Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6-bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53

By similarity.

Catalytic activity: Beta-D-fructose 2,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.

Subunit structure: Monomer

By similarity.

Sequence similarities: Belongs to the phosphoglycerate mutase family.

Caution: Not expected to have any kinase activity.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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