Mouse Anti-FRMD3 Monoclonal Antibody – Cat# MBS6000940

Western Blot detection against Immunogen (35.79kD).

FRMD3 Antibody – Mouse Monoclonal

Name: FRMD3 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6000940
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6000940

Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FRMD3, Monoclonal Antibody

Full Product Name

FRMD3 (EPB41L4O, FERM Domain-containing Protein 3, Band 4.1-like Protein 4O, 4.1O, Ovary Type Protein 4.1, MGC20553, P410)

Product Gene Name

anti-FRMD3 antibody

Product Synonym Names

Anti -FRMD3 (EPB41L4O, FERM Domain-containing Protein 3, Band 4.1-like Protein 4O, 4.1O, Ovary Type Protein 4.1, MGC20553, P410)

Immunogen Sequence

SAPLISSSPV KAAREYEDPP SEEEDKIKEE PLTISELVYN PSASLLPTPV DDDEIDMLFD CPSRLELERE DTDSFEDLEA DENAFLIA

Clonality

Monoclonal

Isotype

IgG2a,k

Clone Number

2F1

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human FRMD3.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

68,772 Da

Chromosome Location

Chromosome: 9; NC_000009.11 (85857905..86153348, complement). Location: 9q21.32

OMIM

607619

3D Structure

ModBase 3D Structure for A2A2Y4

Immunogen

Partial recombinant protein corresponding to aa393-481 from human FRMD3 (NP_777598) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-FRMD3 antibody

Antibodies; Abs to Tumor Suppressors

Applications Tested/Suitable for anti-FRMD3 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-FRMD3 antibody

Suitable for use in ELISA and Western Blot.

Other Notes

Small volumes of anti-FRMD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FRMD3 purchase

MBS6000940 is an antibody targeting FRMD3. Also known as FRMD3 (EPB41L4O, FERM Domain-containing Protein 3, Band 4.1-like Protein 4O, 4.1O, Ovary Type Protein 4.1, MGC20553, P410). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FRMD3. It may not necessarily be applicable to this product.

NCBI GI #

350276220

NCBI GeneID

257019

NCBI Accession #

NP_001231891.1

UniProt Primary Accession #

A2A2Y4

UniProt Secondary Accession #

Q53EP2; Q5JV59; Q5VZA1; Q86WP8; Q8IZ44; Q8N3Y5; Q8N9L2; A8MQB0; B4DN14

UniProt Related Accession #

A2A2Y4

GenBank Nucleotide #

NM_001244962.1

NCBI Official Full Name

FERM domain-containing protein 3 isoform 5

NCBI Official Synonym Full Names

FERM domain containing 3

NCBI Official Symbol

FRMD3

NCBI Official Synonym Symbols

4.1O; P410; EPB41LO; EPB41L4O; RP11-439K3.2

UniProt Protein Name

FERM domain-containing protein 3

UniProt Synonym Protein Names

Band 4.1-like protein 4O; Ovary type protein 4.1

Protein Family

FERM domain-containing protein

UniProt Gene Name

FRMD3

UniProt Synonym Gene Names

EPB41L4O; 4.1O

UniProt Entry Name

FRMD3_HUMAN

NCBI Protein Information

FERM domain-containing protein 3; protein 4.1O; ovary type protein 4.1; band 4.1-like protein 4; band 4.1-like protein 4O

NCBI Summary for FRMD3

The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

UniProt Comments for FRMD3

FRMD3: Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q21.32

Cellular Component: extrinsic to membrane; cytoskeleton; cytoplasm; integral to membrane

Molecular Function: cytoskeletal protein binding

Research Articles on FRMD3

1. These analyses reveal a role for FRMD3 in AA T2DN susceptibility.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-FRMD3 antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>5 publications with FRMD3 and Kidney Diseases
Autoimmune Diseases Antibodies	>2 publications with FRMD3 and Autoimmune Diseases
Neoplasms Antibodies	>2 publications with FRMD3 and Neoplasms
Eye Diseases Antibodies	>1 publications with FRMD3 and Eye Diseases
Lung Neoplasms Antibodies	>1 publications with FRMD3 and Lung Neoplasms

Organs/Tissues associated with anti-FRMD3 antibody

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1 publications with FRMD3 and Skin