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GRID1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6002173

This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GRID1, Polyclonal Antibody
Full Product Name
GRID1, CT (GRID1, KIAA1220, Glutamate receptor delta-1 subunit)
Product Gene Name
anti-GRID1 antibody
Product Synonym Names
Anti -GRID1, CT (GRID1, KIAA1220, Glutamate receptor delta-1 subunit)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
112,131 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (87359312..88126250, complement). Location: 10q22
OMIM
610659
3D Structure
ModBase 3D Structure for Q9ULK0
Immunogen
GRID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 845-875 amino acids from the C-terminal region of human GRID1.

Product Categories/Family for anti-GRID1 antibody

Antibodies; Abs to Receptors
Applications Tested/Suitable for anti-GRID1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GRID1 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-GRID1 antibody

GRID1 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the GRID1 antibody detected the GRID1 protein (arrow).
Rabbit Anti-GRID1 Polyclonal Antibody – Cat# MBS6002173

Immunohistochemistry (IHC) of anti-GRID1 antibody

GRID1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GRID1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-GRID1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6002173

Other Notes

Small volumes of anti-GRID1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GRID1 purchase

MBS6002173 is an antibody targeting GRID1. Also known as GRID1, CT (GRID1, KIAA1220, Glutamate receptor delta-1 subunit). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GRID1. It may not necessarily be applicable to this product.

NCBI GI #
55770852
NCBI GeneID
2894
NCBI Accession #
NP_060021.1
UniProt Primary Accession #
Q9ULK0
UniProt Secondary Accession #
Q8IXT3; B3KXD5
UniProt Related Accession #
Q9ULK0
GenBank Nucleotide #
NM_017551.2
NCBI Official Full Name
glutamate receptor ionotropic, delta-1
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, delta 1
NCBI Official Symbol
GRID1
NCBI Official Synonym Symbols
GluD1
UniProt Protein Name
Glutamate receptor ionotropic, delta-1
Protein Family
Glutamate receptor ionotropic
UniProt Gene Name
GRID1
UniProt Synonym Gene Names
KIAA1220; GluD1
UniProt Entry Name
GRID1_HUMAN
NCBI Protein Information
glutamate receptor ionotropic, delta-1; gluR delta-1 subunit; glutamate receptor delta-1 subunit

UniProt Comments for GRID1

GluR-delta1: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRID1 subfamily.

Protein type: Channel, calcium; Channel, ligand-gated; Receptor, misc.; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q22

Cellular Component: postsynaptic membrane; dendrite; ionotropic glutamate receptor complex; cell junction

Molecular Function: extracellular-glutamate-gated ion channel activity; ionotropic glutamate receptor activity

Biological Process: synaptic transmission, glutamatergic; ionotropic glutamate receptor signaling pathway; social behavior
Show more

Research Articles on GRID1

1. GRID1 genotype is related to gray matter variation in prefrontal and anterior thalamic brain areas in healthy subjects, but not in schizophrenia patients, indicating a potential role in thalamo-cortical functioning.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GRID1 antibody

 Reference Product  PubMed Publications
 GRIK2 antibody  >1 publications with GRID1 and GRIK2

Pathways associated with anti-GRID1 antibody

 Products by Pathway  Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-GRID1 antibody

 Disease Name  Pubmed Publications
 Depressive Disorder Antibodies  >2 publications with GRID1 and Depressive Disorder
 Fetal Death Antibodies  >1 publications with GRID1 and Fetal Death
 Nervous System Malformations Antibodies  >1 publications with GRID1 and Nervous System Malformations
 Nervous System Diseases Antibodies  >1 publications with GRID1 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >1 publications with GRID1 and Congenital Abnormalities
 Breast Neoplasms Antibodies  >1 publications with GRID1 and Breast Neoplasms
 Neoplasms Antibodies  >1 publications with GRID1 and Neoplasms

Organs/Tissues associated with anti-GRID1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with GRID1 and Brain
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