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Formin-Like 1 (FMNL1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600293

MBS600293 is an antibody targeting FMNL1. Also known as Formin-Like 1 (FMNL1, FMNL, C17orf1B, FHOD4, KW-13, MGC1894, MGC21878, MGC133052). Reactive in Human. Host: Mouse. More details

$850 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Formin-Like 1 (FMNL1), Monoclonal Antibody
Full Product Name
Formin-Like 1 (FMNL1, FMNL, C17orf1B, FHOD4, KW-13, MGC1894, MGC21878, MGC133052)
Product Gene Name
Product Synonym Names
Anti -Formin-Like 1 (FMNL1, FMNL, C17orf1B, FHOD4, KW-13, MGC1894, MGC21878, MGC133052)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C148
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human Formin-Like 1.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
121,854 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (43299292..43324685). Location: 17q21
OMIM
604656
3D Structure
ModBase 3D Structure for O95466
Immunogen
Partial sequence of recombinant full-length protein to human Formin-Like 1

Product Categories/Family for anti-FMNL1 antibody

Applications Tested/Suitable for anti-FMNL1 antibody
Western Blot (WB)
Application Notes for anti-FMNL1 antibody
Suitable for use in Western Blotting.
Dilution: Western Blotting: 1:1000-1:2000

Testing Data of anti-FMNL1 antibody

Mouse Anti-FMNL1 Monoclonal Antibody – Cat# MBS600293

Western Blot (WB) of anti-FMNL1 antibody

Detection of human FMNL1 by Western blot. Samples: Whole cell lysate (25 μg) from HeLa cells. Predicted molecular weight: 121 kD
Mouse Anti-FMNL1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS600293

Other Notes

Small volumes of anti-FMNL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FMNL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
formin-like protein 1
NCBI Official Synonym Full Names
formin-like 1
NCBI Official Symbol
FMNL1
NCBI Official Synonym Symbols
FMNL; FHOD4; KW-13; C17orf1; MGC1894; C17orf1B; MGC21878; MGC133052
UniProt Protein Name
Formin-like protein 1
UniProt Synonym Protein Names
CLL-associated antigen KW-13; Leukocyte formin
UniProt Gene Name
FMNL1
UniProt Synonym Gene Names
C17orf1; C17orf1B; FMNL
UniProt Entry Name
FMNL_HUMAN
NCBI Protein Information
formin-like protein 1; leukocyte formin; CLL-associated antigen KW-13

NCBI Summary for FMNL1

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]

UniProt Comments for FMNL1

FMNL1: May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Belongs to the formin homology family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: membrane; plasma membrane; phagocytic vesicle; cell cortex; cytosol

Molecular Function: actin filament binding; protein binding; Rac GTPase binding; GTPase activating protein binding; profilin binding

Biological Process: substrate-bound cell migration; actin filament severing; regulation of cell shape; cortical actin cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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