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SEMA3E Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6002989

Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the… More details

$835 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SEMA3E, Polyclonal Antibody
Full Product Name
SEMA3E (Semaphorin-3E, KIAA0331, SEMAH)
Product Gene Name
Product Synonym Names
Anti -SEMA3E (Semaphorin-3E, KIAA0331, SEMAH)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Canine, Human, Mouse, Porcine, Rat
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SEMA3E. Species sequence homology: Canine, mouse, porcine and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
89,228 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (82993222..83278479, complement). Location: 7q21.11
OMIM
608166
3D Structure
ModBase 3D Structure for O15041
Immunogen
Synthetic peptide corresponding to C-NGGRYGTTKDYPDD, from human SEMA3E, at the internal region of the protein (NP_036563.1, NP_001171600.1).
Applications Tested/Suitable for anti-SEMA3E antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes for anti-SEMA3E antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:128,000
Immunohistochemistry (Paraffin): 4-6ug/ml

Immunohistochemistry (IHC) of anti-SEMA3E antibody

(4ug/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
Goat Anti-SEMA3E Polyclonal Antibody – Cat# MBS6002989

Other Notes

Small volumes of anti-SEMA3E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEMA3E purchase

MBS6002989 is an antibody targeting SEMA3E. Also known as SEMA3E (Semaphorin-3E, KIAA0331, SEMAH). Reactive in Canine, Human, Mouse, Porcine, Rat. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for SEMA3E. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
semaphorin-3E isoform 2
NCBI Official Synonym Full Names
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
NCBI Official Symbol
SEMA3E
NCBI Official Synonym Symbols
SEMAH; coll-5; M-SEMAH; M-SemaK
UniProt Protein Name
Semaphorin-3E
Protein Family
UniProt Gene Name
SEMA3E
UniProt Synonym Gene Names
KIAA0331; SEMAH
UniProt Entry Name
SEM3E_HUMAN
NCBI Protein Information
semaphorin-3E

NCBI Summary for SEMA3E

Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
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UniProt Comments for SEMA3E

SEMA3E: a secreted protein of the semaphorin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 7q21.11

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: protein binding; receptor activity; semaphorin receptor binding

Biological Process: patterning of blood vessels; axon guidance; regulation of cell shape; negative regulation of angiogenesis; synapse organization and biogenesis; sprouting angiogenesis; negative regulation of cell-matrix adhesion

Disease: Charge Syndrome
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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