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Nuclear Factor I/C (NFIC) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600355

MBS600355 is an antibody targeting Nfic. Also known as Nuclear Factor I/C (NFIC, CCAAT-binding Transcription Factor, CTF, CTF5, MGC20153, NF-I). Host: Mouse. More details

$850 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nuclear Factor I/C (Nfic), Monoclonal Antibody
Full Product Name
Nuclear Factor I/C (NFIC, CCAAT-binding Transcription Factor, CTF, CTF5, MGC20153, NF-I)
Product Gene Name
anti-Nfic antibody
Product Synonym Names
Anti -Nuclear Factor I/C (NFIC, CCAAT-binding Transcription Factor, CTF, CTF5, MGC20153, NF-I)
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
8C242
Host
Mouse
Form/Format
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human Nuclear Factor I/C.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
48,742 Da
Chromosome Location
Chromosome: 7; NC_005106.2 (9768135..9793584). Location: 7q11
3D Structure
ModBase 3D Structure for O70188
Immunogen
Partial sequence of recombinant full-length protein to human Nuclear Factor I/C

Product Categories/Family for anti-Nfic antibody

Antibodies; Abs to Transcription Factors
Applications Tested/Suitable for anti-Nfic antibody
Western Blot (WB)
Application Notes for anti-Nfic antibody
Suitable for use in Western Blotting.
Dilution: Western Blotting: 1:1000-1:2000

Testing Data of anti-Nfic antibody

Mouse Anti-NFIC Monoclonal Antibody – Cat# MBS600355

Other Notes

Small volumes of anti-Nfic antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Nfic. It may not necessarily be applicable to this product.

NCBI GI #
148228879
NCBI GeneID
29228
NCBI Accession #
NP_113755.1
UniProt Primary Accession #
O70188
UniProt Related Accession #
O70188; Q9QY87
GenBank Nucleotide #
NM_031567.1
NCBI Official Full Name
nuclear factor 1 C-type
NCBI Official Synonym Full Names
nuclear factor I/C
NCBI Official Symbol
Nfic
NCBI Official Synonym Symbols
Nfic
UniProt Protein Name
Nuclear factor 1
Protein Family
Nuclear factor
UniProt Gene Name
Nfic
UniProt Synonym Gene Names
NF1-C
UniProt Entry Name
O70188_RAT
NCBI Protein Information
nuclear factor 1 C-type; olfactory epithelium nuclear factor I-C

NCBI Summary for Nfic

may regulate gene expression in olfactory neurons [RGD]

UniProt Comments for Nfic

NFI-C: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Cellular Component: nucleoplasm; nucleolus; nucleus

Molecular Function: protein binding; DNA binding; double-stranded DNA binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; sensory perception of smell; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; DNA replication; odontogenesis of dentine-containing teeth
Show more

Research Articles on Nfic

1. gene structure and expression analysis of nuclear factor 1 family in rat

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Nfic antibody

 Products by Pathway  Pathway Diagram
 RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies  RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
 RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies  RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
 RNA Polymerase III Transcription Pathway antibodies  RNA Polymerase III Transcription Pathway Diagram
 RNA Polymerase III Transcription Termination Pathway antibodies  RNA Polymerase III Transcription Termination Pathway Diagram
 Transcription Pathway antibodies  Transcription Pathway Diagram

Diseases associated with anti-Nfic antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with Nfic and Neoplasms
 Carcinoma Antibodies  >3 publications with Nfic and Carcinoma
 Colitis Antibodies  >2 publications with Nfic and Colitis
 Breast Neoplasms Antibodies  >2 publications with Nfic and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with Nfic and Cell Transformation, Neoplastic
 Myocardial Ischemia Antibodies  >1 publications with Nfic and Myocardial Ischemia
 Neoplasms, Hormone-Dependent Antibodies  >1 publications with Nfic and Neoplasms, Hormone-Dependent
 Vascular Diseases Antibodies  >1 publications with Nfic and Vascular Diseases
 Carcinoma, Renal Cell Antibodies  >1 publications with Nfic and Carcinoma, Renal Cell
 Inflammation Antibodies  >1 publications with Nfic and Inflammation

Organs/Tissues associated with anti-Nfic antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >12 publications with Nfic and Brain
 Heart Antibodies  >3 publications with Nfic and Heart
 Nerve Antibodies  >1 publications with Nfic and Nerve
 Muscle Antibodies  >1 publications with Nfic and Muscle
 Connective Tissue Antibodies  >1 publications with Nfic and Connective Tissue
 Eye Antibodies  >1 publications with Nfic and Eye
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