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PRKCBP1 (ZMYND8) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6003886

The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen.… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PRKCBP1 (ZMYND8), Monoclonal Antibody
Full Product Name
PRKCBP1 (Protein Kinase C-binding Protein 1, Rack7, Cutaneous T-cell Lymphoma-associated Antigen se14-3, CTCL-associated Antigen se14-3, ZMYND8, KIAA1125, RACK7)
Product Gene Name
anti-ZMYND8 antibody
Product Synonym Names
Anti -PRKCBP1 (Protein Kinase C-binding Protein 1, Rack7, Cutaneous T-cell Lymphoma-associated Antigen se14-3, CTCL-associated Antigen se14-3, ZMYND8, KIAA1125, RACK7)
Immunogen Sequence
DEQKSKNEPE DTEDKEGCQM DKEPSAVKKK PKPTNPVEIK EELKSTSPAS EKADPGAVKD KASPEPEKDF SEKAKPSPHP IKDKLKGKDE TDSPTVHL*
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
5B12
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human PRKCBP1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
131,692 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (45837994..45985485, complement). Location: 20q13.12
3D Structure
ModBase 3D Structure for Q9ULU4
Immunogen
Partial recombinant corresponding to aa601-699 from PRKCBP1 (NP_898869) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-ZMYND8 antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-ZMYND8 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ZMYND8 antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 0.25ug/ml

Western Blot (WB) of anti-ZMYND8 antibody

Western Blot detection against Immunogen (36.89kD).
Mouse Anti-ZMYND8 Monoclonal Antibody – Cat# MBS6003886

Western Blot (WB) of anti-ZMYND8 antibody

PRKCBP1 monoclonal antibody. Western Blot analysis of PRKCBP1 expression in Hela NE.
Mouse Anti-ZMYND8 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6003886

Immunohistochemistry (IHC) of anti-ZMYND8 antibody

Immunoperoxidase of monoclonal antibody to ZMYND8 on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 0.25ug/ml]
Mouse Anti-ZMYND8 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6003886

Testing Data of anti-ZMYND8 antibody

Detection limit for recombinant GST tagged PRKCBP1 is ~0.03ng/ml as a capture antibody.
Mouse Anti-ZMYND8 Monoclonal Antibody, Testing Data – Cat# MBS6003886

Other Notes

Small volumes of anti-ZMYND8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZMYND8 purchase

MBS6003886 is an antibody targeting ZMYND8. Also known as PRKCBP1 (Protein Kinase C-binding Protein 1, Rack7, Cutaneous T-cell Lymphoma-associated Antigen se14-3, CTCL-associated Antigen se14-3, ZMYND8, KIAA1125, RACK7). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ZMYND8. It may not necessarily be applicable to this product.

NCBI GI #
528881309
NCBI GeneID
23613
NCBI Accession #
NP_001268709.1
UniProt Primary Accession #
Q9ULU4
UniProt Secondary Accession #
Q13517; Q2HXV2; Q2HXV7; Q2HXV8; Q2HXW0; Q2HXW1; Q2HXW2; Q4JJ94; Q4JJ95; B7Z680; E1P5U5
UniProt Related Accession #
Q9ULU4
GenBank Nucleotide #
NM_001281780.1
NCBI Official Full Name
protein kinase C-binding protein 1 isoform n
NCBI Official Synonym Full Names
zinc finger, MYND-type containing 8
NCBI Official Symbol
ZMYND8
NCBI Official Synonym Symbols
RACK7; PRKCBP1; PRO2893
UniProt Protein Name
Protein kinase C-binding protein 1
UniProt Synonym Protein Names
Cutaneous T-cell lymphoma-associated antigen se14-3; CTCL-associated antigen se14-3; Rack7; Zinc finger MYND domain-containing protein 8
Protein Family
Protein kinase C-binding protein
UniProt Gene Name
ZMYND8
UniProt Synonym Gene Names
KIAA1125; PRKCBP1; RACK7; CTCL-associated antigen se14-3
UniProt Entry Name
PKCB1_HUMAN
NCBI Protein Information
protein kinase C-binding protein 1; CTCL tumor antigen se14-3; predicted protein of HQ2893; zinc finger MYND domain-containing protein 8; cutaneous T-cell lymphoma-associated antigen se14-3

UniProt Comments for ZMYND8

RACK7: a DNA damage response (DDR) protein, receptor for activated C-kinase (RACK) protein, and a transcriptional regulator. A bromodomain (BRD)-containing protein that recruits the nucleosome remodeling and histone deacetylation (NuRD) complex to damaged chromatin. Targets DNA damage within actively transcribed regions, repressing transcription, and promoting repair by homologous recombination. A cutaneous T-cell lymphoma-associated antigen that contains a bromodomain and two zinc fingers. Twenty-two alternatively spliced isoforms of the human protein hve been reported. Note: This description may include information from UniProtKB

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: nucleus

Molecular Function: protein binding; zinc ion binding

Biological Process: negative regulation of transcription from RNA polymerase II promoter
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Research Articles on ZMYND8

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ZMYND8 antibody

 Products by Pathway  Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram

Diseases associated with anti-ZMYND8 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with ZMYND8 and Neoplasms
 Uterine Cervical Neoplasms Antibodies  >1 publications with ZMYND8 and Uterine Cervical Neoplasms
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